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Morphological and Functional Peculiarities of Lymphoid Cells in Mice of Different Strains

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Abstract

We revealed differences in quantitative composition and functional activity of lymphoid cells in intact mice of different strains. Cellularity and counts of lymphoid elements in hemopoietic and lymphoid organs, proliferative activity of T and B lymphocytes, and counts of CD4+ and CD8+ lymphocytes in the spleen were minimum in CC57W and Balb/c mice and maximum in CBA/CaLac and DBA/2 mice. The highest absolute content of lymphoid elements in the spleen was detected in Balb/c mice, while CC57W mice had the highest content of these elements in the thymus.

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Authors and Affiliations

  1. Institute of Pharmacology, Tomsk Research Center, Siberian Division of Russian Academy of Medical Sciences, Russia

    E. D. Goldberg, N. V. Masnaya & A. A. Churin

Authors
  1. E. D. Goldberg
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  2. N. V. Masnaya
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  3. A. A. Churin
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Goldberg, E.D., Masnaya, N.V. & Churin, A.A. Morphological and Functional Peculiarities of Lymphoid Cells in Mice of Different Strains. Bulletin of Experimental Biology and Medicine 137, 622–624 (2004). https://doi.org/10.1023/B:BEBM.0000042728.04244.e4

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  • DOI: https://doi.org/10.1023/B:BEBM.0000042728.04244.e4

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