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Preclinical Study of the Effect of Cardiotropic Agents on Isolated Heart

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Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

Direct effects of cardiotropic preparations on the hearts isolated from Wistar rats were examined. Deenergization of cardiomyocytes was modeled under conditions of hypoxic perfusion. Recovery of cardiac function during reperfusion was assessed by changes in the heart rate and contraction amplitude.

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Authors and Affiliations

  1. Institute of Theoretical and Experimental Biophysics, Russian Academy of Sciences, Pushchino

    D. V. Goldshtein, A. A. Zakaryan, V. S. Kuzmin, A. G. Pogorelov, G. S. Sukhova & E. V. Khrenova

  2. Department of Biology, M. V. Lomonosov Moscow State University, Russia

    D. V. Goldshtein, A. A. Zakaryan, V. S. Kuzmin, A. G. Pogorelov, G. S. Sukhova & E. V. Khrenova

Authors
  1. D. V. Goldshtein
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  2. A. A. Zakaryan
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  3. V. S. Kuzmin
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  4. A. G. Pogorelov
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  5. G. S. Sukhova
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  6. E. V. Khrenova
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Goldshtein, D.V., Zakaryan, A.A., Kuzmin, V.S. et al. Preclinical Study of the Effect of Cardiotropic Agents on Isolated Heart. Bulletin of Experimental Biology and Medicine 137, 566–567 (2004). https://doi.org/10.1023/B:BEBM.0000042713.18766.4d

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  • DOI: https://doi.org/10.1023/B:BEBM.0000042713.18766.4d

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