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Wound-Healing Effect of Papaya-Based Preparation in Experimental Thermal Trauma

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Abstract

Treatment with the phytopreparation from papaya accelerated wound healing and reduced the severity of local inflammation in rats with burn wounds. The effect of this phytopreparation can be related to an increase in the effectiveness of intracellular bacterial killing by tissue phagocytes due to the inhibition of bacterial catalase. Antioxidant activity of the preparation decreases the risk of oxidative damage to tissues.

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REFERENCES

  1. O. V. Bukharin, S. V. Cherkasov, A. V. Sgibnev, et al., Byull. Eksp. Biol. Med., 130, No. 7, 80-82 (2000).

    Google Scholar 

  2. E. V. Mikhal'chik, L. G. Korkina, S. D. Shiyan, and N. G. Bovin, Biol. Membrany, 11, 581-587 (1994).

    Google Scholar 

  3. N. A. Busch, E. M. Zanzot, P. M. Loiselle, et al., Infect. Immun., 68, No. 6, 3349-3351 (2000).

    PubMed  Google Scholar 

  4. R. A. Greenwald, Handbook of Methods for Oxygen Radical Research, Florida (1986), pp. 291-302.

  5. H. P. Misra and I. Fridovich, J. Biol. Chem., 247, 3170-3175 (1972).

    PubMed  Google Scholar 

  6. S. L. Nielsen, F. T Black, M. Storgaard, and N. Obel, J. Biochem., 118, 271-277 (1995).

    PubMed  Google Scholar 

  7. J. A. Osato, I. B. Afanas'ev, Z. P. Cheremisina, et al., Phys. Chem. Biol. Med., 2, 87-95 (1995).

    Google Scholar 

  8. I. F. Starley, P. Mohammed, G. Schneider, and S. W. Bickler, Burns, 25, No. 7, 636-639 (1999).

    PubMed  Google Scholar 

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Authors and Affiliations

  1. Department of Molecular Biology, Department of Physiology, Russian State Medical University, Russia

    E. V. Mikhalchik, A. V. Ivanova, M. V. Anurov, S. M. Titkova, L. Yu. Penkov, Z. F. Kharaeva & L. G. Korkina

  2. Department of Surgery, Institute of Pediatrics and Child Surgery, Russian Ministry of Health, Child Municipal Clinical Hospital No. 9, Moscow

    E. V. Mikhalchik, A. V. Ivanova, M. V. Anurov, S. M. Titkova, L. Yu. Penkov, Z. F. Kharaeva & L. G. Korkina

  3. Kabardino-Balkarian State University, Nalchik

    E. V. Mikhalchik, A. V. Ivanova, M. V. Anurov, S. M. Titkova, L. Yu. Penkov, Z. F. Kharaeva & L. G. Korkina

Authors
  1. E. V. Mikhalchik
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  2. A. V. Ivanova
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  3. M. V. Anurov
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  4. S. M. Titkova
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  5. L. Yu. Penkov
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  6. Z. F. Kharaeva
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  7. L. G. Korkina
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Mikhalchik, E.V., Ivanova, A.V., Anurov, M.V. et al. Wound-Healing Effect of Papaya-Based Preparation in Experimental Thermal Trauma. Bulletin of Experimental Biology and Medicine 137, 560–562 (2004). https://doi.org/10.1023/B:BEBM.0000042711.31775.f7

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  • DOI: https://doi.org/10.1023/B:BEBM.0000042711.31775.f7

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