Abstract
Immobilization stress for 14 h induced lymphopenia, hypoplasia of the thymus and spleen, and decrease in functional activity of T lymphocytes and macrophages in C57Bl/6 mice. Active induction of antibodies against serotonin during stress decreased functional activity of T lymphocytes and partially recovered phagocytic activity of peritoneal macrophages.
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REFERENCES
T. V. Davydova, V. A. Evseev, V. G. Fomina, et al., Patol. Fiziol. Eksper. Ter., No. 2, 10-12 (1998).
T. V. Davydova, V. G. Fomina, L. A. Basharova, et al., Byull. Eksp. Biol. Med., 124, No. 9, 292-295 (1997).
L. V. Devoino and R. Yu. Il'yuchenok, Neurotransmitter Systems in Psychoneuroimmunomodulation [in Russian], Novosibirsk (1993).
V. A. Evseev, L. A. Basharova, L. A. Vetrile, et al., Byull. Eksp. Biol. Med., 122, No. 8, 189-192 (1996).
V. A. Evseev, T. V. Davydova, V. G. Fomina, and L. A. Vetrile, Ibid., 112, No. 7, 33-34 (1991).
V. A. Evseev, T. V. Davydova, V. G. Fomina, and L. A. Vetrile, Ibid., 116, No. 7, 582-584 (1993).
V. A. Evseev, N. A. Trekova, L. A. Vetrile, et al., Ibid., 132, No. 7, 26-29 (2001).
A. A. Churin, N. V. Masnaya, O. S. Borsuk, and E. Yu. Sherstoboev, Ibid., 136, No. 9, 304-308 (2003).
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Davydova, T.V., Fomina, V.G., Vetrile, L.A. et al. Immunotropic Effects of Active Immunization with Serotonin-Protein Conjugate in C57Bl/6 Mice Exposed to Immobilization Stress. Bulletin of Experimental Biology and Medicine 137, 535–537 (2004). https://doi.org/10.1023/B:BEBM.0000042704.51389.d6
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DOI: https://doi.org/10.1023/B:BEBM.0000042704.51389.d6