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Immunohistochemical Study of Fetal Stem/Progenitor Cells from Human Brain Transplanted into Traumatized Spinal Cord of Adult Rats

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Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

Neural stem/progenitor cells from human fetal brain were grown in a tissue culture and transplanted into traumatized spinal cord of adult rats. The behavior and differentiation of transplanted cells were studied morphologically by means of histological and immunohistochemical methods and confocal microscopy. Human neural stem/progenitor cells were viable for not less than 3 months. They migrated and differentiated into neurons and glia in the traumatized spinal cord of adult rats.

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Authors and Affiliations

  1. N. K. Koltsov Institute of Developmental Biology, Russian Academy of Sciences, Russia

    O. V. Podgornyi, M. V. Marey, D. O. Karpenko, M. A. Aleksandrova, R. A. Poltavtseva, A. V. Revishchin, G. A. Stepanov & G. T. Sukhikh

  2. Center for Obstetrics, Gynecology, and Perinatology, Russian Academy of Medical Sciences, Russia

    O. V. Podgornyi, M. V. Marey, D. O. Karpenko, M. A. Aleksandrova, R. A. Poltavtseva, A. V. Revishchin, G. A. Stepanov & G. T. Sukhikh

  3. Central Institute of Traumatology and Orthopedics, Russia

    O. V. Podgornyi, M. V. Marey, D. O. Karpenko, M. A. Aleksandrova, R. A. Poltavtseva, A. V. Revishchin, G. A. Stepanov & G. T. Sukhikh

  4. Institute for Problems of Ecology and Evolution, Russian Academy of Sciences, Moscow

    O. V. Podgornyi, M. V. Marey, D. O. Karpenko, M. A. Aleksandrova, R. A. Poltavtseva, A. V. Revishchin, G. A. Stepanov & G. T. Sukhikh

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  1. O. V. Podgornyi
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  2. M. V. Marey
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  3. D. O. Karpenko
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  4. M. A. Aleksandrova
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  5. R. A. Poltavtseva
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  6. A. V. Revishchin
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  7. G. A. Stepanov
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  8. G. T. Sukhikh
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Podgornyi, O.V., Marey, M.V., Karpenko, D.O. et al. Immunohistochemical Study of Fetal Stem/Progenitor Cells from Human Brain Transplanted into Traumatized Spinal Cord of Adult Rats. Bulletin of Experimental Biology and Medicine 137, 415–418 (2004). https://doi.org/10.1023/B:BEBM.0000035146.81784.05

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  • DOI: https://doi.org/10.1023/B:BEBM.0000035146.81784.05

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