Abstract
Dimephosphone injected on days 1-19 of gestation did not cause fetal death and specific abnormalities in rats and did not modulate sex differentiation of fetuses. Morphological study of fetal liver revealed no pathological changes.
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REFERENCES
S. N. Golikov and V. I. Rozengart, Cholinesterase and Anticholinesterase Agents [in Russian], Moscow (1964).
A. A. Gumerova, I. Kh. Valeeva, and A. P. Kiyasov, Ontogenez, 30, No. 4, 289-295 (1999).
Yu. S. Kagan, Toxicology of Organophosphorus Pesticides and Hygiene of Labor for Their Use [in Russian], Moscow (1963).
A. P. Kiryushenkov and M. L. Tarakhovskii, Effects of Drugs, Ethanol, and Nicotine on the Fetus [in Russian], Moscow (1990).
R. Kh. Khafiz'yanova, Kazansk. Med. Zh., No. 3, 169-171 (1994).
R. Kh. Khafiz'yanova, I. A. Studentsova, V. I. Danilov, et al., Ibid., No. 1, 8-12 (1993).
N. A. Chebotar', L. A. Konopistseva, T. V. Ignat'eva, et al., Tsitol. Genet., 28, No. 5, 77-80 (1994).
S. C. Gad, Statistics and Experimental Design for Toxicologists, Boca Raton (1999).
J. C. Kim, H. C. Shin, S. W. Cha, et al., Life Sci., 69, 2611-2625 (2001).
D. H. Minsker, J. M. Manson, and C. P. Peter, Toxicol. Appl. Pharmacol., 121, Mo. 2, 217-223 (1993).
N. Patlas, G. Golomb, P. Yaffe, et al., Teratology, 60, 68-73 (1999).
J. E. Polifka and K. L. Jones, Immunol. Allergy Clin North Am., 20, No. 11, 81-92 (2000).
J. Vassy, T. Irinopoulou, M. Beil, and J. P. Rigaut, Microsc. Res. Tech., 39, No. 5, 436-443 (1997).
Y. Yoshishige, F. Pornpoj, T. Yukihiko, et al., Arch. Oral Biol., 45, No. 3, 207-215 (2000).
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Khafizyanova, R.K., Burykin, I.M., Aleeva, G.N. et al. Effect of Dimephosphone (Monophosphonate) on the Course of Pregnancy and Fetal Development in Rats. Bulletin of Experimental Biology and Medicine 137, 375–378 (2004). https://doi.org/10.1023/B:BEBM.0000035135.22484.2a
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DOI: https://doi.org/10.1023/B:BEBM.0000035135.22484.2a