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Human Neural Stem Cells Normalize Rat Behavior after Hypoxia

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Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

Transplants of cultured neural stem cells from human brain survived, retained multipotent activity, and produced a neuroprotective effect on degenerating neurons in the brain of adult rats subjected to hypoxic hypoxia. They normalized animal behavior and improved conditioning in two-way avoidance response paradigm in a shuttle box.

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Authors and Affiliations

  1. N. K. Koltsov Institute of Developmental Biology, Russian, Academy of Sciences, Moscow

    O. V. Podgornyi, I. V. Kheifets, M. A. Aleksandrova, E. V. Loseva, A. V. Revishchin, R. A. Poltavtseva, M. V. Marey, L. I. Korochkin & G. T. Sukhikh

  2. Institute of Higher Nervous Activity and Neurophysiology, Russian Academy of Sciences, Moscow

    O. V. Podgornyi, I. V. Kheifets, M. A. Aleksandrova, E. V. Loseva, A. V. Revishchin, R. A. Poltavtseva, M. V. Marey, L. I. Korochkin & G. T. Sukhikh

  3. Institute of Gene Biology, Russian Academy of Sciences, Moscow

    O. V. Podgornyi, I. V. Kheifets, M. A. Aleksandrova, E. V. Loseva, A. V. Revishchin, R. A. Poltavtseva, M. V. Marey, L. I. Korochkin & G. T. Sukhikh

  4. Center for Obstetrics, Gynecology, and Perinatology, Russian Academy of Medical Sciences, Moscow

    O. V. Podgornyi, I. V. Kheifets, M. A. Aleksandrova, E. V. Loseva, A. V. Revishchin, R. A. Poltavtseva, M. V. Marey, L. I. Korochkin & G. T. Sukhikh

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  1. O. V. Podgornyi
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  2. I. V. Kheifets
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  3. M. A. Aleksandrova
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  4. E. V. Loseva
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  5. A. V. Revishchin
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  6. R. A. Poltavtseva
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  7. M. V. Marey
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  8. L. I. Korochkin
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  9. G. T. Sukhikh
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Podgornyi, O.V., Kheifets, I.V., Aleksandrova, M.A. et al. Human Neural Stem Cells Normalize Rat Behavior after Hypoxia. Bulletin of Experimental Biology and Medicine 137, 348–351 (2004). https://doi.org/10.1023/B:BEBM.0000035126.42951.44

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  • DOI: https://doi.org/10.1023/B:BEBM.0000035126.42951.44

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