Skip to main content
SpringerLink
Log in

Cytotoxic Activity of Endometrial Immunocompetent Cells Determines the Outcome of Embryo Implantation

  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

The data on the formation of blastocysts in culture during therapeutic cycles of extracorporeal fertilization and on cytotoxic index of the endometrium in women with different clinical pathogenetic variants of sterility are presented. Analysis of correlations of these parameters with the incidence of effective implantation and pregnancy revealed a strict correlation between cytotoxic activity of endometrial immunocompetent cells and human embryo implantation.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

REFERENCES

  1. O. A. Vorob'eva, A. A. Kirsanov, and V. V. Potin, Probl. Reproduktsii, No. 4, 17–21 (1999).

  2. L. S. Hewdice, Probl. Endokrinol., No. 5, 30–32 (1999).

  3. V. I. Kulakov and V. N. Serov, Manual of the Reproductive Health Protection [in Russian], Moscow (2001).

  4. A. V. Svetlakov, M. V. Yamanova, A. B. Salmina, and O. A. Serebrennikova, Probl. Reproduktsii, No. 3, 61–67 (2002).

  5. A. M. Fes'kov, Ukr. Med. Zh., No. 5, 120–123 (2000).

  6. V. N. Ellinidi, N. V. Anikeeva, and N. A. Maksimova, Practical Immunohistochemistry [in Russian], St. Petersburg (2002), P. 36.

  7. P. C. Arck, K. Hertwig, E. Hagen, et al., Am. J. Reprod. Immunol., 44, No. 1, 1–8 (2000).

    Google Scholar 

  8. A. Arici, E. Oral, O. Bukulmez, et al., Fertil. Steril., 65, No. 3, 603–607 (1996).

    Google Scholar 

  9. N. Garrido, J. Navarro, J. Remohi, et al., Hum. Reprod. Update, 6, No. 1, 67–74 (2000).

    Google Scholar 

  10. H. N. Ho, K. H. Chao, C. K. Chen, et al., Hum. Immunol., 49, No. 2, 130–136 (1996).

    Google Scholar 

  11. R. K. Hones, J. N. Bulmer, and R. F. Searle, Biol. Reprod., 57, No. 6, 1217–1222 (1997).

    Google Scholar 

  12. P. M. Johnson, S. E. Christmas, and G. S. Vince, Hum. Reprod., 14, No. 2, 26–36 (1999).

    Google Scholar 

  13. S. Quenby, M. Bates, T. J. Doig, et al.,Hum. Reprod., No. 9, 2386-2391.

  14. E. V. Royen, K. Mangelschots, D. D. Neubourg, et al., Hum. Reprod., 2345-2349.

  15. M. Sandalinas, S. Sadowy, M. Alicani, et al., Hum. Reprod., 16, No. 9, 1954–1958 (2001).

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Center of Reproductive Medicine, Krasnoyarsk; All-Russian Center of Emergency and Radiation Medicine, Ministry of Emergency Situations of Russia, Krasnoyarsk State Medical Academy, St. Petersburg

    M. V. Yamanova, A. B. Salmina, A. V. Svetlakov, V. N. Ellinidi, N. V. Anikeeva, O. A. Serebrennikova & I. I. Evdochenko

Authors
  1. M. V. Yamanova
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. A. B. Salmina
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. A. V. Svetlakov
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. V. N. Ellinidi
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. N. V. Anikeeva
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. O. A. Serebrennikova
    View author publications

    You can also search for this author in PubMed Google Scholar

  7. I. I. Evdochenko
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Yamanova, M.V., Salmina, A.B., Svetlakov, A.V. et al. Cytotoxic Activity of Endometrial Immunocompetent Cells Determines the Outcome of Embryo Implantation. Bulletin of Experimental Biology and Medicine 137, 82–85 (2004). https://doi.org/10.1023/B:BEBM.0000024394.56974.c3

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1023/B:BEBM.0000024394.56974.c3

Search

Navigation