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Experimental Mycoplasma hominis Infection of the Genital Tract in BALB/c Mice

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Abstract

We studied the ability of laboratory and clinical strains of Mycoplasma hominis to colonize the genital tract mucosa in BALB/c mice. Colonization with mycoplasma occurred only in mice receiving estrogen. Mycoplasma hominis strains obtained after 3-fold passage through the vaginal mucosa in mice and administered intravaginally in a dose of 0.5×108 CFU/ml caused infection in 100% animals. Inflammation in the lower genital tract was reduced by the 8th week after infection.

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Authors and Affiliations

  1. Institute of Physicochemical Medicine, Russian Ministry of Health, Moscow

    M. M. Shkarupeta, V. N. Lazarev & V. M. Govorun

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  1. M. M. Shkarupeta
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  2. V. N. Lazarev
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  3. V. M. Govorun
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Shkarupeta, M.M., Lazarev, V.N. & Govorun, V.M. Experimental Mycoplasma hominis Infection of the Genital Tract in BALB/c Mice. Bulletin of Experimental Biology and Medicine 137, 53–55 (2004). https://doi.org/10.1023/B:BEBM.0000024386.33789.0f

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  • DOI: https://doi.org/10.1023/B:BEBM.0000024386.33789.0f

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