Skip to main content
Log in

Modification of Baroreceptor Cardiac Reflex Function by Biofeedback

  • Published:
Applied Psychophysiology and Biofeedback Aims and scope Submit manuscript

Abstract

Baroreceptor sensitivity (BRS) is considered a powerful prognostic factor in cardiovascular health. This study investigated the possibility of modifying the baroreflex cardiac function through biofeedback. Thirty-two psychology students underwent 3 biofeedback sessions, with four 5-min trials each, in which they had to increase and decrease baroreflex function. BRS was assessed by a system that analyzed baroreflex cardiac function on-line using a noninvasive spontaneous sequence method in the time domain. Baroreceptor parameters were differentiated in terms of blood pressure increases (“up” sequences) or blood pressure decreases (“down” sequences). BRS in the “up” sequences increased during the Increase Condition and decreased during the Decrease Condition. BRS in the “down” sequences decreased during the Decrease Condition but was unchanged during the Increase Condition. The increase in BRS during the Increase Condition was associated with a significant reduction in blood pressure and increase in heart period. The opposite cardiovascular changes were observed during the Decrease Condition. Suggestions for future research were discussed.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

REFERENCES

  • Berntson, G. G., Bigger, J. T., Eckberg, D. L., Grossman, P., Kaufmann, P. G., Malik, M., et al. (1997). Heart rate variability: Origins, methods, and interpretative caveats. Psychophysiology, 34 ,623–648.

    PubMed  Google Scholar 

  • Bertinieri, G., di Rienzo, M., Parati, B., Pomidossi, G., Pedotti, A., Zanchetti, A., et al. (1987). Baroreceptor-heart rate reflex studied in normotensive and essential hypertensives by beat-to-beat analysis of 24-hour blood pressure and heart rate. Journal of Hypertension, 5 ,5333–5335.

    Google Scholar 

  • Conway, J. (1984). Hemodynamic aspects of essential hypertension in humans. Physiological Reviews, 64 ,617–660.

    PubMed  Google Scholar 

  • de Boer, R. W., Karemaker, J. M., & Strackee, J. (1987). Hemodynamic fluctuations and baroreflex sensitivity in humans: A beat-to-beat model. American Journal of Physiology, 249 ,H867–H875.

    Google Scholar 

  • Eckberg, D. L., Kifle, Y. T., & Roberts, V. L. (1980). Phase relationship between human respiration and baroreflex responsiveness. Journal of Physiology, 304 ,489–502.

    PubMed  Google Scholar 

  • Eckberg, D. L., & Sleight, P. (1992). Human baroreflexes in health and disease. Oxford, UK: Oxford University Press.

    Google Scholar 

  • Engel, B. T., & Joseph, J. A. (1982). Attenuation of baroreflexes during operant cardiac conditioning. Psychophysiology, 19 ,609–614.

    PubMed  Google Scholar 

  • González, M. I., & Reyes del Paso, G. A. (1999). Self-control of baroreceptor cardiac reflex sensitivity. Psychophysiology, 36 ,S55.

    Google Scholar 

  • Gribbin, B., Pickering, T. G., Sleight, P., & Peto, R. (1971). Effect of age and high blood pressure on baroreflex sensitivity in man. Circulation Research, 29 ,424–431.

    PubMed  Google Scholar 

  • Grossman, P. (1983). Respiration, stress, and cardiovascular function. Psychophysiology, 20 ,284–300.

    PubMed  Google Scholar 

  • Grossman, P., Brinkman, A., & de Vries, J. (1992). Cardiac autonomic mechanisms associated with borderline hypertension under varying bahavioral demands: Evidence for attenuated parasympathetic tone but not for enhanced beta-adrenergic activity. Psychophysiology, 29 ,698–711.

    PubMed  Google Scholar 

  • Iwase, N., Takata, S., Okuwa, H., Ogawa, J., Ikeda, T., & Hattori, N. (1984). Abnormal baroreflex control of heart rate in normotensive young subjects with a family history of essential hypertension. Journal of Hypertension, 2 ,409–411.

    Google Scholar 

  • Kleiger, R. E., Miller, J. P., Bigger, J. T., & Moss, A. J. (1987). Decreased heart rate variability and its association with increased mortality after acute myocardial infarction. American Journal of Cardiology, 59 ,256–262.

    Article  PubMed  Google Scholar 

  • Lacey, J., & Lacey, B. (1970). Some autonomic-central nervous system interrelationships. In P. Black (Ed.), Physiological correlates of emotion (pp. 205–277). New York: Academic Press.

    Google Scholar 

  • La Rovere, M. T., Bigger, T. J., Marcus, F. I., Mortara, A., Schwartz, P. J. for the ATRAMI (Autonomic Tone and Reflexes After Myocardial Infarction) investigators. (1998). Baroreflex sensitivity and heart rate variability in prediction of total cardiac mortality after myocardial infarction. Lancet, 351 ,478–484.

    Article  PubMed  Google Scholar 

  • Lal, S. K. L., Henderson, R. J., Carter, N., Bath, A., Hart, M. G., Langeluddecke, P., et al. (1998). Effect of feedback signal and psychological characteristic on blood pressure self-manipulation capability. Psychohysiology, 35 ,405–412.

    Google Scholar 

  • Lehrer, P., Carr, R. E., Smetankine, A., Vaschillo, E., Peper, E., Porges, S., et al. (1997). Respiratory sinus arrhythmia versus neck/trapezius EMG and incentive inspirometry biofeedback for asthma: A pilot study. Applied Psychophysiology and Biofeedback, 22 ,95–101.

    Article  PubMed  Google Scholar 

  • Lehrer, P.M., Vaschillo, E., & Vaschillo, B. (2000). Resonant frequency training to increase heart cardiac variability: Rationale and manual for training. Applied Psychophysiology and Biofeedback, 25 ,177–191.

    Article  PubMed  Google Scholar 

  • Lucini, D., Covacci, G., Milani, R., Mela, G. S., Malliani, A., & Pagani, M. (1997). A controlled study of the effects of mental relaxation on autonomic excitatory responses in healthy subjects. Psychosomatic Medicine, 59 ,541–552.

    PubMed  Google Scholar 

  • Nakao, M., Nomura, S., Shimosawa, T., Yoshiuchi, K., Kumano, H., Kuboki, T., et al. (1997). Clinical effects of blood pressure biofeedback treatment on hypertension by auto-shaping. Psychosomatic Medicine, 59 ,331–338.

    PubMed  Google Scholar 

  • Parmer, R. J., Hustine, H., Cervenka, R. T., & Stone, R. A. (1992). Baroreflex sensitivity and heredity in essential hypertension. Circulation, 85 ,497–503.

    PubMed  Google Scholar 

  • Piepoli, M., Sleight, P., Leuzzi, S., Valle, F., Spadacini, G., Passino, C., et al. (1997). Origin of respiratory sinus arrhythmia in conscious humans. An important role for arterial carotid baroreceptors. Circulation, 95 ,1813–1821.

    PubMed  Google Scholar 

  • Reyes del Paso, G. A. (1992). An on-line program to calculate respiratory sinus arrhythmia amplitude. Behavior Research Methods, Instruments, and Computers, 24 ,464–466.

    Google Scholar 

  • Reyes del Paso, G. A. (1994). A program to assess baroreceptor cardiac reflex function. Behavior Research Methods, Instruments, and Computers, 26 ,62–64.

    Google Scholar 

  • Reyes del Paso, G. A. (1999). Abiofeedback system of baroreceptor cardiac reflex sensitivity. Applied Psychophysiology and Biofeedback, 24 ,67–77.

    Article  PubMed  Google Scholar 

  • Reyes del Paso, G. A., & García, A. (1993). Registro y análisis computarizado de la actividad respiratoria y el sinus arritmia respiratorio. Psicológica, 14,355–366.

    Google Scholar 

  • Reyes del Paso, G. A., Langewitz, W., Robles, H., & Pérez, N. (1996). A between-subjects comparison of respiratory sinus arrhythmia and baroreceptor cardiac reflex sensitivity as non-invasive measures of tonic parasympathetic cardiac control. International Journal of Psychophysiology, 22 ,163–171.

    Article  PubMed  Google Scholar 

  • Robbe, H. W. J., Mulder, L. J. M., Rüddel, H., Veldman, J. B. P., Langewitz, W. A., & Mulder, G. (1987). Assessment of baroreflex sensitivity by means of spectral analysis. Hypertension, 10 ,538–543.

    PubMed  Google Scholar 

  • Sakakibara, M., & Hayano, J. (1995). Effect of slowed respiration on cardiac parasympathetic response to threat. Psychosomatic Medicine, 58 ,32–37.

    Google Scholar 

  • Sakakibara, M., Takeuchi, S., & Hayano, J. (1994). Effect of relaxation on cardiac parasympathetic tone. Psychophysiology, 31 ,223–228.

    PubMed  Google Scholar 

  • Sleight, P. (1997). The importance of the autonomic nervous system in health and disease. Australian and New Zealand Journal of Medicine, 27 ,467–473.

    PubMed  Google Scholar 

  • Sleight, P., La Rovere, M. T., Mortara, A., Pinna, G., Maestri, R., Leuzzi, S., et al. (1995). Physiology and pathophysiology of heart rate and blood pressure variability in humans: Is power spectral analysis largely an index of baroreceptor gain?. Clinical Science, 88 ,103–109.

    PubMed  Google Scholar 

  • Sloan, R. P., Shapiro, P. A., Bagiella, E., Myers, M. M., & Gorman, J. M. (1999). Cardiac autonomic control buffers blood pressure variability responses to challenge: A psychophysiological model of coronary artery disease. Psychosomatic Medicine, 61 ,58–68.

    PubMed  Google Scholar 

  • Steptoe, A., & Sawada, Y. (1989). Assessment of baroreceptor reflex function during mental stress and relaxation. Psychophysiology, 26 ,140–147.

    PubMed  Google Scholar 

  • Steptoe, A., & Vögele, C. (1990). Cardiac baroreflex function during postural change assessed using non-invasive spontaneous sequence analysis in young men. Cardiovascular Research, 24 ,627–632.

    PubMed  Google Scholar 

  • Stoney, C. M., Davis, M. C., & Matthews, K.A. (1987). Sex differences in physiological responses to stress and in coronary heart disease: A causal link?. Psychophysiology, 24 ,127–131.

    PubMed  Google Scholar 

  • Victor, R. G., & Morgan, B. (1990). Baroreceptors and hypertension. Circulation, 82 ,1057–1059.

    PubMed  Google Scholar 

  • Whelton P. K. (1994). Epidemiology of hypertensión. Lancet, 344 ,101–106.

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Gustavo A. Reyes del Paso.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Reyes del Paso, G.A., González, M.I. Modification of Baroreceptor Cardiac Reflex Function by Biofeedback. Appl Psychophysiol Biofeedback 29, 197–211 (2004). https://doi.org/10.1023/B:APBI.0000039058.68746.ad

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1023/B:APBI.0000039058.68746.ad

Navigation