Acta Biotheoretica

, Volume 52, Issue 3, pp 201–217 | Cite as

Current Issues in Statistics and Models for Ecotoxicological Risk Assessment

  • Nelly van der Hoeven


A review is given on statistical and modelling issues in ecotoxicology. The issues discussed are:

1. How to estimate an (almost) no effect concentration chemicals in the laboratory.

2. Combining single-species acceptable effect levels to an acceptable effect level for a multi-species ecosystem.

3. The combined effect of exposure to several chemicals.

4. Bioavailability in the natural environment and food-web models.

Most current procedures in setting standards allow the environmental concentration to be above the acceptable effect concentration for a small fraction of the species. It is shown that a considerable part of the fraction of the affected species will suffer a severe effect.

bioaccumulation bioavailability combination toxicology ECx equilibrium partition food-web models hazardous concentration NOEC Species Sensitivity Distribution Toxic Units 


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Copyright information

© Kluwer Academic Publishers 2004

Authors and Affiliations

  • Nelly van der Hoeven
    • 1
  1. 1.ECOSTATInstitute of Biology, Leiden University2300 RA LeidenThe Netherlands

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