Somatic Cell and Molecular Genetics

, Volume 25, Issue 1, pp 33–39 | Cite as

The Human RNA Helicase A (DDX9) Gene Maps to the Prostate Cancer Susceptibility Locus at Chromosome Band 1q25 and Its Pseudogene (DDX9P) to 13q22, Respectively

  • Chee-Gun Lee
  • Toshihiko Eki
  • Katsuzumi Okumura
  • Masahiro Nogami
  • Vera da Costa Soares
  • Yasufumi Murakami
  • Fumio Hanaoka
  • Jerard Hurwitz


RNA helicase A is the homolog of the Drosophila maleless protein, an essential factor involved in dosage compensation, and plays a crucial role in early development in mammals. Here, we have mapped the human RNA helicase A (DDX9) gene to the major susceptibility locus for prostate cancer at chromosome band 1q25, and its pseudogene (DDX9P) to the band 13q22 by fluorescence in situ hybridization, somatic cell hybrid analysis, and assignment of YAC clones, respectively.


Prostate Cancer Somatic Cell Early Development Cancer Susceptibility Cell Hybrid 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Plenum Publishing Corporation 1999

Authors and Affiliations

  • Chee-Gun Lee
    • 1
  • Toshihiko Eki
    • 2
  • Katsuzumi Okumura
    • 3
  • Masahiro Nogami
    • 3
  • Vera da Costa Soares
    • 1
  • Yasufumi Murakami
    • 2
  • Fumio Hanaoka
    • 2
  • Jerard Hurwitz
    • 1
  1. 1.Graduate Program in Molecular BiologyMemorial Sloan-Kettering Cancer CenterNew York
  2. 2.Cellular Physiology LaboratoryThe Institute of Physical and Chemical Research (RIKEN)SaitamaJapan
  3. 3.Faculty of BioresourcesMie University, TsuMieJapan

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