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Application of Gas Chromatography and Gas Chromatography–Mass Spectrometry to the Detection of γ-Hydroxybutyric Acid and Its Precursors in Various Materials

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Abstract

Modified procedures were developed for the detection of γ-hydroxybutyric acid and 1,4-butanediol (its metabolic precursor) in foods, food additives, and urine using gas chromatography and gas chromatography–mass spectrometry. The analytical range was 0.1–20 wt %.

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Authors and Affiliations

  1. 111th Center of Forensic Medical and Criminalistic Examination, Ministry of Defense of the Russian Federation, Gospital'naya pl. 3, Moscow, 105229, Russia

    E. A. Simonov

  2. GU Criminalistic Examination Center, Ministry of Internal Affairs of the Russian Federation, ul. Z. i A. Kosmodem'yanskikh 5, Moscow, 125130, Russia

    V. I. Sorokin

  3. Vernadsky Institute of Geochemistry and Analytical Chemistry, Russian Academy of Sciences, ul. Kosygina 19, Moscow, 119991, Russia

    S. A. Savchuk

Authors
  1. E. A. Simonov
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  2. V. I. Sorokin
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  3. S. A. Savchuk
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Simonov, E.A., Sorokin, V.I. & Savchuk, S.A. Application of Gas Chromatography and Gas Chromatography–Mass Spectrometry to the Detection of γ-Hydroxybutyric Acid and Its Precursors in Various Materials. Journal of Analytical Chemistry 59, 965–971 (2004). https://doi.org/10.1023/B:JANC.0000043913.31843.62

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  • DOI: https://doi.org/10.1023/B:JANC.0000043913.31843.62

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