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Journal of Analytical Chemistry

, Volume 59, Issue 3, pp 288–290 | Cite as

Electrochemical Determination of Lipoic Acid

  • G. K. Ziyatdinova
  • G. K. Budnikov
  • V. I. Pogorel'tsev
Article

Abstract

Procedures for determining lipoic acid by voltammetry and coulometric titration with electrogenerated halogens using the biamperometric indication of the titration end-point were developed. Possible mechanisms of lipoic acid oxidation with electrogenerated halogens are discussed. Microgram amounts of lipoic acid were determined in model solutions with an RSD of 1–2%. The analytical range of lipoic acid found by voltammetry at a glassy-carbon electrode lies between 1.15 × 10–5 and 1.73 × 10–4 M. The detection limit for lipoic acid is 5.75 × 10–6 M.

Keywords

Oxidation Analytical Chemistry Titration Detection Limit Halogen 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© MAIK “Nauka/Interperiodica” 2004

Authors and Affiliations

  • G. K. Ziyatdinova
    • 1
  • G. K. Budnikov
    • 1
  • V. I. Pogorel'tsev
    • 2
  1. 1.Department of ChemistryKazan State UniversityTatarstanRussia
  2. 2.Kazan State Medical UniversityTatarstanRussia

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