Chemistry of Heterocyclic Compounds

, Volume 40, Issue 7, pp 869–875 | Cite as

Reaction of 3,5-Carbonyl-substituted 1,4-Dihydropyridines with Hydrazine Hydrate

  • E. Bisenieks
  • J. Uldrikis
  • G. Duburs


The interaction of 3,5-carbonyl-substituted derivatives of 1,4-dihydropyridine and some analogs of it with hydrazine hydrate occurs with fission of the heterocycle. In the case of alkoxycarbonyl-substituted compounds a reverse Michael reaction predominates leading to fragmentation of the molecules.

3-acyl- and 3-alkoxycarbonyl-5-oxo-1,4-dihydroindeno[1,2-b]pyridines 3,5-acyl- and 3,5-alkoxycarbonyl-1,4-dihydropyridines pyrazole derivatives fission of heterocycle with hydrazine 


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Copyright information

© Plenum Publishing Corporation 2004

Authors and Affiliations

  • E. Bisenieks
    • 1
  • J. Uldrikis
    • 1
  • G. Duburs
    • 1
  1. 1.Latvian Institute of Organic SynthesisRiga LVUSA

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