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Method for Determining the Characteristics of an Epithermal-Neutron Beam for Boron-Neutron-Capture Therapy

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Abstract

Epithermal neutrons are used in boron-neutron-capture therapy to remove multiform glioblastomas and deep-lying melanoma tumors. Thermal neutrons interact with 10B which is preintroduced as a pharmacological preparation. The reaction products kill malignant tumor cells.

A beam of epithermal neutrons from a nuclear reactor is formed using collimators and specially assembled additional moderators. A method where detectors with 235U, screened by 10B with different thickness and placed in a vertical array perpendicular to the beam, is proposed for obtaining real-time information. The neutron flux near ΔE i and the spectrum in a wide range are determined from the difference of the signals from before and after detectors.

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Authors and Affiliations

  1. State Science Center of the Russian Federation –, TRINITI, Russia

    Yu. A. Kashchuk, V. V. Frunze & D. V. Prosvirin

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  1. Yu. A. Kashchuk
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  2. V. V. Frunze
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  3. D. V. Prosvirin
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Kashchuk, Y.A., Frunze, V.V. & Prosvirin, D.V. Method for Determining the Characteristics of an Epithermal-Neutron Beam for Boron-Neutron-Capture Therapy. Atomic Energy 96, 52–56 (2004). https://doi.org/10.1023/B:ATEN.0000022814.22066.cb

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  • DOI: https://doi.org/10.1023/B:ATEN.0000022814.22066.cb

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