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Oxidative Damage and Fragmentation of Mitochondrial DNA in Cellular Apoptosis

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Abstract

The molecular genetics and bioenergetics of oxidative damage, fragmentation, and fragility of mitochondrial DNA in cellular apoptosis is reviewed in connection with the “redox mechanism of ageing”.

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  1. Department of Biomedical Chemistry, Faculty of Medicine, University of Nagoya, Nagoya, 466, Japan

    Takayuki Ozawa

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Ozawa, T. Oxidative Damage and Fragmentation of Mitochondrial DNA in Cellular Apoptosis. Biosci Rep 17, 237–250 (1997). https://doi.org/10.1023/A:1027324410022

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