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A Preliminary Study on the Anthelmintic Activity of Calotropis procera Latex against Haemonchus contortus Infection in Najdi Sheep

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Abstract

The anthelmintic activity of Calotropis procera latex was investigated in sheep that had been infected with single oral doses of 12 000 infective Haemonchus contortus larvae. Inappetence, dullness, erosive abomasitis, decreased haemoglobin concentration and increased eosinophils were the main features of haemonchosis in the sheep. In the sheep treated with single oral doses of 0.01 ml or 0.02 ml/kg body weight of C. procera latex, egg production was significantly reduced, but not completely suppressed, and fewer adult Haemonchus worms were found in the abomasum. Although the appetite improved, the haemoglobin concentration and serum copper, iron and zinc levels were still reduced after therapy with Calotropis latex. Calotropis latex showed a concentration-dependent larvicidal activity in vitro within 20 min of application.

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REFERENCES

  • Ageel, A.M., Mossa, J.S., Al-Yahya, M.A., Tariq, M. and Al-Said, M.S., 1987. Plants Used in Folk Medicine, (King Saud University Press, Riyadh)

    Google Scholar 

  • Al-Yahya, M.A., Al-Meshal, I.A., Mossa, J.S., Al-Badr, A.A. and Tariq, M., 1990. Saudi Plants: A Phytochemical and Biological Approach, (King Saud University Press, Riyadh)

    Google Scholar 

  • Downey, N.E. and Connolly, J.F., 1963. Methods for the enumeration of trichostrongylid third-stage larvae. Journal of Helminthology, 37, 255-260

    Google Scholar 

  • El-Badwi, S.M.A., 1997. Toxicological studies on latex ofmedicinal plants: Calotropis procera, Ficus elastica and Euphorbia abyssinica, (PhD thesis, University of Khartoum, Khartoum)

  • Hammond, J.A., Fielding, D. and Bishop, S.C., 1997. Prospects of plant anthelmintics in tropical veterinary medicine.Veterinary Research Communications, 21, 213-228

    Google Scholar 

  • Khan, A.Q. and Abdul Malik, A., 1989. A steroid from Calotropis procera. Phytochemistry, 28, 2834-2862

    Google Scholar 

  • Larhsini, M., Bousaid, M., Lazrek, H.B. and Jana, M., 1997. Evaluation of antifungal and molluscicidal properties of extract of Calotropis procera. Fitoterapia, 68, 371-373

    Google Scholar 

  • Mahmoud, O.M., Adam, S.E.I. and Tartour, G., 1979. The effect of Calotropis procera on small ruminants. 2. Effect of administration of the latex to sheep and goats. Journal of Comparative Pathology, 89, 251-256

    Google Scholar 

  • SAS Institute, 1996. SAS/STAT Users Guide,Volume 2, 4th edn, (SAS Institute Inc., Cary, NC)

    Google Scholar 

  • Schalm, O.W., Jain, N.C. and Carroll, G.H., 1975. Veterinary Haematology, 3rd edn, (Lea and Febiger, Philadelphia)

    Google Scholar 

  • Soulsby, E.J.L., 1982. Helminths, Arthropods and Protozoa of Domesticated Animals, 7th edn, (Baillieère Tindall and Cassell, London)

    Google Scholar 

  • Watt, J.M. and Breyer-Brandwijk, N.G., 1962. Medicinal and Poisonous Plants of Southern and Eastern Africa, 2nd edn, (Livingstone, Edinburgh)

    Google Scholar 

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Authors and Affiliations

  1. Department of Veterinary Medicine, College of Agriculture and Veterinary Medicine, King Saud University, PO Box 1482, Buraydah, Al-Qassim, Saudi Arabia

    A.A. Al-Qarawi, O.M. Mahmoud, M.A. Sobaih, E.M. Haroun & S.E.I. Adam

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  1. A.A. Al-Qarawi
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  2. O.M. Mahmoud
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  3. M.A. Sobaih
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  4. E.M. Haroun
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  5. S.E.I. Adam
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Al-Qarawi, A., Mahmoud, O., Sobaih, M. et al. A Preliminary Study on the Anthelmintic Activity of Calotropis procera Latex against Haemonchus contortus Infection in Najdi Sheep. Vet Res Commun 25, 61–70 (2001). https://doi.org/10.1023/A:1026762002947

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  • DOI: https://doi.org/10.1023/A:1026762002947

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