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From Gel Filtration to Adsorptive Size Exclusion

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Abstract

Adsorption and size exclusion in starch and cross-linked dextran were phenomena discovered in Uppsala in the 1950s [Porath (1979), Biochem. Soc. Trans. 7, 1197; Porath (1981), Current Content 19, 21; Porath (1981), J. Chromatogr. 218, 241; Janson (1987), Chromatographia 23, 361; Laurent (1993), J. Chromatogr. 633, 1]. These discoveries were the background to the development of a variety of affinity chromatographic methods. At present attempts are being made to combine size exclusion chromatography (SEC) with adsorption into a single operation that we call adsorptive SEC (AdSEC).

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Porath, J. From Gel Filtration to Adsorptive Size Exclusion. J Protein Chem 16, 463–468 (1997). https://doi.org/10.1023/A:1026357326667

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  • DOI: https://doi.org/10.1023/A:1026357326667

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