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Secure web book to store structural genomics research data

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Journal of Structural and Functional Genomics

Abstract

Recently established collaborative structural genomics programs aim at significantly accelerating the crystal structure analysis of proteins. These large-scale projects require efficient data management systems to ensure seamless collaboration between different groups of scientists working towards the same goal. Within the Berlin-based Protein Structure Factory, the synchrotron X-ray data collection and the subsequent crystal structure analysis tasks are located at BESSY, a third-generation synchrotron source. To organize file-based communication and data transfer at the BESSY site of the Protein Structure Factory, we have developed the web-based BCLIMS, the BESSY Crystallography Laboratory Information Management System. BCLIMS is a relational data management system which is powered by MySQL as the database engine and Apache HTTP as the web server. The database interface routines are written in Python programing language. The software is freely available to academic users. Here we describe the storage, retrieval and manipulation of laboratory information, mainly pertaining to the synchrotron X-ray diffraction experiments and the subsequent protein structure analysis, using BCLIMS.

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Authors and Affiliations

  1. Protein Structure Factory, c/o BESSY GmbH, Albert-Einstein Str.15, 12489, Berlin, Germany

    Babu A. Manjasetty, Klaus Höppner & Uwe Mueller

  2. Forschungsgruppe Kristallographie, Max-Delbrück-Centrum für Molekulare Medizin, Robert-Rössle Str. 10, 13092, Berlin, Germany

    Babu A. Manjasetty & Udo Heinemann

  3. Department of Physics, Government Science College, Bangalore, 560 012, India

    Babu A. Manjasetty

  4. Institut für Chemie/Kristallographie, Freie Universität, Takustr. 6, 14195, Berlin, Germany

    Klaus Höppner & Udo Heinemann

Authors
  1. Babu A. Manjasetty
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  2. Klaus Höppner
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  3. Uwe Mueller
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  4. Udo Heinemann
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Manjasetty, B.A., Höppner, K., Mueller, U. et al. Secure web book to store structural genomics research data. J Struct Func Genom 4, 121–127 (2003). https://doi.org/10.1023/A:1026169519592

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  • DOI: https://doi.org/10.1023/A:1026169519592

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