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Photochemical Processes in Aqueous Solutions of Immunoactive 8-Azasteroid

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Journal of Applied Spectroscopy Aims and scope

Abstract

Based on an analysis of the absorption, fluorescence excitation, and fluorescence spectra, and the duration of the excited states of an aqueous solution (pH 7.4) of 2,3-dimethoxy-8-azagona-1,3,5(10),13-tetraen-12,17-dione molecules, the existence of two centers emitting longwave (L centers) and shortwave (S centers) fluorescence has been established. Irradiation of the solution accelerates the accumulation of L centers and considerably reduces the quantity of S centers that represent the initial molecule. Analysis of the induced-absorption spectra and their kinetics with picosecond time resolution shows that ionization of the molecule studied is the initial photochemical act and formation of a dehydro derivative of the initial molecule or protonation of carbonyl groups is the next act.

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Authors and Affiliations

  1. Institute of Molecular and Atomic Physics, National Academy of Sciences of Belarus, 70 F. Skorina Ave., Minsk, 220072, Belarus

    N. A. Borisevich, V. L. Dubovskii, T. F. Raichenok, S. A. Tikhomirov & G. B. Tolstorozhev

  2. Institute of Bioorganic Chemistry, National Academy of Sciences of Belarus, Minsk, Belarus

    A. L. Mikhal'chuk

Authors
  1. N. A. Borisevich
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  2. V. L. Dubovskii
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  3. A. L. Mikhal'chuk
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  4. T. F. Raichenok
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  5. S. A. Tikhomirov
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  6. G. B. Tolstorozhev
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Borisevich, N.A., Dubovskii, V.L., Mikhal'chuk, A.L. et al. Photochemical Processes in Aqueous Solutions of Immunoactive 8-Azasteroid. Journal of Applied Spectroscopy 70, 545–549 (2003). https://doi.org/10.1023/A:1026146430668

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  • DOI: https://doi.org/10.1023/A:1026146430668

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