Abstract
The effect of pH (over the range of 2.10 - 11.90) and temperature (from 353 K to 363 K) on the stability of xylometazoline (XYL) has been studied by high performance liquid chromatography (HPLC). Using the dependence of log k vs pH, the hydrolysis of both the undissociated and dissociated XYL-molcules has been described by micro rate constants k1 and k2. Thermodynamic parameters (activation energy, enthalpy and entropy) of the composition reaction were calculated.
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Stanisz, B. Kinetics of hydrolysis of xylometazoline (XYL) in aqueous solution. Reaction Kinetics and Catalysis Letters 80, 67–73 (2003). https://doi.org/10.1023/A:1026076024274
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DOI: https://doi.org/10.1023/A:1026076024274