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Working Memory and On-Line Sentence Comprehension in Patients with Alzheimer's Disease

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Abstract

We examined the ability of patients with dementia of the Alzheimer's type (DAT) and normal controls to perform a sentence acceptability judgment task that required determining the referent for a reflexive pronoun. Performance on three different sentence types that differed in terms of syntactic complexity was assessed. Subjects performed the task alone and under two different dual-task conditions which required continuous, externally paced responses. DAT patients were more affected than controls by the dual-task conditions, but were not disproportionately impaired on the more complex sentence types. The failure of DAT patients to he disproportionately affected on the most complex sentence types in the dual-task conditions provides evidence for the separation of the processing resources that are used in sentence comprehension from those involved in other tasks.

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REFERENCES

  • The Army Individual Test Battery (Trailmaking subtest). (1944). Tucson, AZ: Reitan Neuropsychology Laboratory.

  • Baddeley, A. D. (1976). The psychology of memory. New York: Basic Books.

    Google Scholar 

  • Baddeley, A. D. (1986). Working memory. Oxford, England: Clarendon Press.

    Google Scholar 

  • Baddeley, A. D., Bressi, S., Della Sala, S., Logie, R., & Spinnler, H. (1991). The decline of working memory in Alzheimer's Disease. Brain, 114, 2521–2542.

    Google Scholar 

  • Baddeley, A. D., Della Sala, S., & Spinnler, H. (1991). The two-component hypothesis of memory deficits in Alzheimer's disease. Journal of Clinical and Experimental Neuropsychology, 13, 372–380.

    Google Scholar 

  • Baddeley, A. D., & Hitch, G. (1974). Working memory. In G. H. Bower (Ed.), The psychology of learning and motivation (Vol. 8, pp. 47–89). San Diego, CA: Academic Press.

    Google Scholar 

  • Baddeley, A. D., Logie, R., Bressi, S., Della Sala, S., & Spinnler, H. (1986). Dementia and working memory. The Quarterly Journal of Experimental Psychology, 38A, 603–618.

    Google Scholar 

  • Benton, A. L. (1974). Revised visual retention test (4th edition). New York: The Psychological Corporation.

    Google Scholar 

  • Blessed, G., Tomlinson, B. E., & Roth, M. (1968). The association between quantitative measures of dementia and of senile change in the cerebral grey matter of elderly subjects. American Journal of Psychiatry, 114, 797–811.

    Google Scholar 

  • Caplan, D., Hildebrandt, N. & Waters, G. S. (1994). Interaction of verb selectional restrictions, noun animacy, and syntactic form in sentence processing. Language and Cognitive Processes, 9, 549–585.

    Google Scholar 

  • Caplan, D., & Waters, G. S. (1990). Short-term memory and language comprehension: A critical review of the neuropsychological literature. In G. Vallar & T. Shallice (Eds.), Neuropsychological impairments of short-term memory (pp. 337–389). Cambridge, England: Cambridge University Press.

    Google Scholar 

  • Caplan, D., & Waters, G. S. (1995). Aphasic disturbances of syntactic comprehension and working memory capacity. Cognitive Neuropsychology, 12, 637–649.

    Google Scholar 

  • Chomsky, N. (1986). Knowledge of language. New York: Praeger.

    Google Scholar 

  • Daneman, M., & Carpenter, P. A. (1980). Individual differences in working memory and reading. Journal of Verbal Learning and Verbal Behavior, 19, 450–468.

    Google Scholar 

  • Fodor, J. A. (1983). The modularity of mind. Cambridge, MA: MIT Press.

    Google Scholar 

  • Folstein, M. F. & Folstein, S. E. (1975). “Mini-Mental State”: A practical method for grading the cognitive state of patients for the clinician. Journal of Psychiatric Research, 12, 189–198.

    Google Scholar 

  • Golden, C. J. (1978). Color and Word Test. Woodale, Illinois: Stoelting Co.

    Google Scholar 

  • Goodglass, H. & Kaplan, E. (1983). Boston Naming Test, Malvern, Pennsylvania: Lea & Febiger.

    Google Scholar 

  • Just, M., & Carpenter, P. A. (1992). A capacity theory of comprehension. Psychological Review, 99, 122–149.

    Google Scholar 

  • King, J., & Just, M. A. (1991). Individual differences in syntactic processing: The role of working memory: Journal of Memory and Language, 30, 580–602.

    Google Scholar 

  • MacDonald, M. C., Just, M., & Carpenter, P. A. (1992). Working memory constraints on the processing of syntactic ambiguity. Cognitive Psychology, 24, 56–98.

    Google Scholar 

  • Martin, R. C. (1990). Neuropsychological evidence on the role of short-term memory in sentence processing. In G. Vallar & T. Shallice (Eds.), Neuropsychological impairments of short-term memory (pp. 390–427). Cambridge, England: Cambridge University Press.

    Google Scholar 

  • Martin, R. C. (1993). Short-term memory and sentence processing: Evidence from neuropsychology. Memory & Cognition, 21, 176–183.

    Google Scholar 

  • Mattis, S. (1976). Mental status examination for organic mental syndrome in the elderly patient. In L. Bellack & T. Karasu (Eds.), Geriatric psychiatry (pp. 77–121) New York: Grune.

    Google Scholar 

  • McKhann, G., Drachman, D., Folstein, M., Katzman, R., Price, D., & Stadlan, E. M. (1984). Clinical diagnosis of Alzheimer's disease: Report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease. Neurology, 34, 939–944.

    Google Scholar 

  • Mertis, J. (1989). Bliss user's manual. Providence, RI: Brown University.

    Google Scholar 

  • Morris, J. C., Heyman, A., Mohs, R. C., Hughes, J. P., van Belle, G., Filenbaum, G., Mellitas, E. D., Clark, C., & the CERAD investigators (1989). The consortium to establish a registry for Alzheimer's disease (CERAD). Part I. Clinical and neuropsychological assessment of Alzheimer's disease. Neurology, 39, 1159–1165.

    Google Scholar 

  • Morris, R. G. (1984). Dementia and the functioning of the articulatory loop system. Cognitive Neuropsychology, 1, 143–157.

    Google Scholar 

  • Morris, R. G. (1986). Short-term forgetting in senile dementia of the Alzheimer's type. Cognitive Neuropsychology, 3, 77–97.

    Google Scholar 

  • Morris, R. G. (1987). Articulatory rehearsal in Alzheimer's type dementia. Brain and Language, 30, 351–362.

    Google Scholar 

  • Morris, R. G. & Baddeley, A. D. (1988). Primary and working memory functioning in Alzheimer's-type dementia. Neurology, 8, 544–554.

    Google Scholar 

  • Murtha, S., Chertkow, H., Waters, G. S., Laurent, C., & Bergman, H. (1997). Working memory impairment in dementia of the Alzheimer's type (DAT): Evidence against a single Central Executive? Manuscript submitted for publication.

  • Osborne, D. P. Jr., Brown, E. R., & Randt, C. T. (1992). Qualitative changes in memory function: aging and dementia. Alzheimer's Disease: A report of progress. In S. Corkin (Ed). Aging, New York: Raven Press.

    Google Scholar 

  • Reinhart, T. (1983). Anaphora and semantic interpretation. London, England: Croom Helm.

    Google Scholar 

  • Rochon, E., Waters, G., & Caplan, D. (1994). Sentence comprehension in patients with Alzheimer's disease. Brain & Language, 46, 329–349.

    Google Scholar 

  • Rochon, E., Waters, G., & Caplan, D. (1997). The relationship between measures of working memory and sentence comprehension in patients with Alzheimer's disease. Manuscript submitted for publication.

  • Shah, P. & Miyake, A. (1996). The separability of working memory resources for spatial thinking and language processing: An individual differences approach. Journal of Experimental Psychology: General, 251, 4–27.

    Google Scholar 

  • Thal, L. J., Grundman, M., & Golden, R. (1986). Alzheimer's disease: A correlational analysis of the Blessed-Information-Memory-Concentration Test and the Mini-Mental State Exam. Neurology, 36, 262–264.

    Google Scholar 

  • Waters, G. S., & Caplan, D. (1996a). Processing resource capacity and the comprehension of garden path sentences. Memory & Cognition, 24, 342–355.

    Google Scholar 

  • Waters, G. S., & Caplan (1996b). The measurement of verbal working memory capacity and its relation to reading comprehension. Quarterly Journal of Experimental Psychology, 49A, 51–79.

    Google Scholar 

  • Waters, G. S., & Caplan, D. (1996c). The Capacity Theory of sentence comprehension: A critique of Just & Carpenter (1992). Psychological Review, 103, 761–772.

    Google Scholar 

  • Waters, G. S., Caplan, D., & Hildebrandt, N. (1987). Working memory and written sentence comprehension. In M. Coltheart (Ed.), Attention and performance, vol. 12, The psychology of reading. Lawrence Erlbaum, Hillsdale, New Jersey, pp. 531–555.

    Google Scholar 

  • Waters, G. S., Caplan, D., & Hildebrandt, N. (1991). On the structure of verbal STM and its functional role in sentence comprehension: A case study. Cognitive Neuropsychology, 8, 81–126.

    Google Scholar 

  • Waters, G. S., Caplan, D., & Rochon, E. (1995). Processing capacity and sentence comprehension in patients with Alzheimer's disease. Cognitive Neuropsychology, 12, 1–30.

    Google Scholar 

  • Waters, G. S., Komoda, M. K., & Arbuckle, T. Y. (1985). The effects of concurrent tasks on reading: Implications for phonological 2. Journal of Memory and Language, 24, 27–45.

    Google Scholar 

  • Wechsler, D. (1981). Wechsler Adult Intelligence Scale-Revised. San Antonio; The Psychological Corporation, Harcourt, Brace, Jovanovich.

    Google Scholar 

  • Wechsler, D. (1987). Wechsler Memory Scale-Revised. San Antonio; The Psychological Corporation, Harcourt, Brace, Jovanovich.

    Google Scholar 

  • Wisconsin Card Sorting Test. (1993). Odessa, FL; Psychological Assessment Resources.

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Authors and Affiliations

  1. School of Communication Sciences and Disorders, McGill University, Montreal, Quebec, H3G 1A8, Canada

    Gloria S. Waters

  2. Neuropsychology Laboratory, Neurology Department, Massachusetts General Hospital, Boston, Massachusetts, 02114

    David Caplan

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  1. Gloria S. Waters
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  2. David Caplan
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Waters, G.S., Caplan, D. Working Memory and On-Line Sentence Comprehension in Patients with Alzheimer's Disease. J Psycholinguist Res 26, 377–400 (1997). https://doi.org/10.1023/A:1025073902269

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