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Pathomorphology of the Vascular Bed of Postinfarction Heart in Various Types of Remodeling

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Abstract

We evaluated pathomorphological changes in the vascular bed of postinfarction heart in various types of remodeling. Dilatational remodeling was characterized by dilation of coronary arteries, increase in their volume density, and regular arrangement. Signs of coronary blood flow reduction and microcirculatory disturbances in the left ventricle were revealed during hypertrophic remodeling. Aneurysmal remodeling was characterized by the presence of small-vascular collateral-anastomotic plexus and reduction of the microcirculatory bed. Endocardial remodeling was accompanied by hypervascularization of the myocardium, formation of new coronary vessels, and reduced capillarization in the left ventricle of postinfarction heart.

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Authors and Affiliations

  1. Department of General Pathology and Pathomorphology, Institute of Regional Pathology and Pathomorphology, Siberian Division of the Russian Academy of Medical Sciences, Novosibirsk

    V. D. Rozenberg & L. M. Nepomnyashchikh

Authors
  1. V. D. Rozenberg
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  2. L. M. Nepomnyashchikh
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Correspondence to L. M. Nepomnyashchikh.

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Rozenberg, V.D., Nepomnyashchikh, L.M. Pathomorphology of the Vascular Bed of Postinfarction Heart in Various Types of Remodeling. Bulletin of Experimental Biology and Medicine 135, 503–508 (2003). https://doi.org/10.1023/A:1024935913730

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  • DOI: https://doi.org/10.1023/A:1024935913730

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