Abstract
Large-scale production of radioisotopes for medical application was impeded by limited capabilities of the electromagnetic separation. Nowadays the centrifuge separation process involves more than two dozens of chemical elements. The cost of isotopes is incomparably lower than of those produced by electromagnetic separation, which has made enriched isotopes more practicable and has extended their application scope. The development of new isotope targets has ensured the realization of more effective schemes of 123I production. The processes of 124Xe and 123Te production are reviewed.
Similar content being viewed by others
References
E. I. Abbakumov et al., At. Energy, 67 (1989) 255 (in Russian).
V. A. Khalkin et al., Radiokhimiya, 29 (1987) 391 (in Russian). Stable isotopes, Mound Laboratory, Catalog, 1977, p. 47.
V. I. Levin et al., On the iodine-123 production technique. SU invention, No. 671194, 1977.
I. K. Kikoin et al., Iodine-123 production on a linear electron accelerator with the use of xenon-124 of high enrichment. Production techniques of iodine-123 and radiopharmaceuticals on its basis, Proc Conf., Moscow, March 18-19, 1986, p. 18 (in Russian).
E. Coester et al., Production of stable isotopes by gas centrifuge, 4th Intern. Symp. on the Synthesis and Applications of Isotopes and Isotopically Labelled Compounds, Toronto, Canada, 1991, p. 1.
Fu Zhuge, Jingyan Wu, The study of multicomponent separation of Xe isotopes with centrifugal method. Separation Phenomena in Liquids and Gases, 5th Workshop Proceedings, C. Schwab et al. (Eds), Foz do Iguacu, Brasil, 1996, p. 98.
I. A. Suvorov, A. N. Tcheltsov, Nucl. Instr. Meth., A334 (1993) 33.
V. A. Khalkin, A. V. Tikhomirov, Radionuclide iodine-123 production technique. SU invention, No. 1597005, 1988.
L. Andy et al., J. Radioanal. Nucl. Chem., 146 (1990) 169.
A. N. Shubin et al., The production of high purity Te-123 isotope for Iodine-123. 3rd Intern. Conf. on Isotope Production and Application in the 21st Century, Vancouver, Canada, Sept. 6-10, 1999, Conference Handbook & Abstracts, Report No. J.50.
B. K. Kudelin, L. M. Solin, V. A. Jakovlev, Experience in iodine-123 production via p,n reaction. Synthesis and Applications of Isotopically Labeled Compounds, Vol. 7, Proc. 7th Intern. Symp., Dresden, Germany 18-22 June 2000, U. Pleiss and R. Voges (Eds), J. Wiley & Sons Ltd., p. 37.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Tikhomirov, A.V. Enriched stable isotopes for 123I production: Pathways and prospects. Journal of Radioanalytical and Nuclear Chemistry 257, 157–160 (2003). https://doi.org/10.1023/A:1024774116402
Issue Date:
DOI: https://doi.org/10.1023/A:1024774116402