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Fluorescence Enhancement of Aflatoxins Using Native and Substituted Cyclodextrins

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Abstract

Cyclodextrins have been used as fluorescence enhancers in HPLC to improve thedetection limits of aflatoxins, cancerogens which can be found in severalfoodstuffs. In this work, a screening of several cyclodextrins has been performedin order to find the factors affecting the fluorescence enhancement. Evidence for formationof a 1 : 1 AF-CD inclusion complex has been achieved by titration and competitiveexperiments with adamantanecarboxylic acid and by fluorescence quenching by KI.Stability constants of the AF-CD complexes were evaluated.

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Dall'asta, C., Ingletto, G., Corradini, R. et al. Fluorescence Enhancement of Aflatoxins Using Native and Substituted Cyclodextrins. Journal of Inclusion Phenomena 45, 257–263 (2003). https://doi.org/10.1023/A:1024572426577

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  • DOI: https://doi.org/10.1023/A:1024572426577

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