Abstract
Effects of recombinant β-carotene on the resistance of E. coli culture to menadione and paraquat were studied. The presence of β-carotene in E. coli cells prevented, to a considerable extent, an increase in superoxide dismutase activity (induced by redox mediators) without affecting the culture growth. These findings suggest that β-carotene is involved in the defense of cells against oxidative stress.
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REFERENCES
Britton, G., FASEB J., 1995, vol. 9, no.15, pp. 1551–1558.
Olson, J.A., Ann. N. Y. Acad. Sci., 1993, vol. 691, pp. 156–166.
Crabtree, D.V. and Adler, A.J., Med. Hypothesis, 1997, vol. 48, no.2, pp. 183–187.
Young, A.E. and Lowe, E.M., Arch. Biochem. Biophys., 2001, vol. 38, no.1, pp. 20–27.
Liochev, S.I. and Fridovich, I., Arch. Biochem. Biophys., 1992, vol. 294, no.1, pp. 138–143.
Gort, A.S. and Imlay, J.A., J. Bacteriol., 1998, vol. 180, no.6, pp. 1402–1410.
Imlay, J.A. and Fridovich, I., Arch. Biochem. Biophys., 1992, vol. 296, no.2, pp. 337–346.
Gaudu, P., Moon, N., and Weiss, B., J. Biol. Chem., 1997, vol. 272, no.9, pp. 5082–5086.
Sun, Z., Gantt, E., and Cunningham, F.X., Jr., J. Biol. Chem., 1996, vol. 271, no.40, pp. 24349–24352.
Sambrook, J., Fritsch, E.F., and Maniatis, T., Molecular Cloning: a Laboratory Manual, New York: Cold Spring Harbor, Lab. Press, 1989, vol. 3; Appendix, A.1.
Kostyuk, V.A., Potapovich, A.I., and Kovaleva, Zh.V., Voprosy med. khimii, 1990, vol. 36, no.2, pp. 88–91.
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Gessler, N.N., Sokolov, A.V. & Belozerskaya, T.A. Involvement of β-Carotene in the Antioxidant Defense of the Bacterial Cell. Applied Biochemistry and Microbiology 39, 382–384 (2003). https://doi.org/10.1023/A:1024516417479
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DOI: https://doi.org/10.1023/A:1024516417479