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Evidence of Toscana virus circulation in Umbria: First report

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Abstract

To evaluate, for the first time, circulation and clinical expression of Toscana virus (ToSv) in Umbria region we studied: (1) 93 cases of aseptic meningitis and meningoencephalitis admitted to our Department from 1989 to 2001 with negative results for common neurotropic virus; (2) 50 healthy subjects. Specific antibodies (IgM and IgG) anti-TOSv were found in 36.6% of aseptic meningitis, in 6.06% of meningoencephalitis and (IgG) in 16% of healthy subjects.

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References

  1. Paci P, Balducci M, Verani P, et al. Toscana virus, a new phlebotomus transmittedvirus isolatedin Italy. Proceeding of International Congress for Infectious Diseases, Vienna 1984: 34–39.

  2. Verani P, Lopes MC, Nicoletti L, Balducci M. Studies on phlebotomus-transmittedviruses in Italy. Isolation andcharacterization of a sandfly fever Naples-like virus. In: Vesenjak-Hirjan J, Porterfield JS, Arslanagic E (eds), Arboviruses in the Mediterranean Countries. Stuttgart: Gusta Fischer Verlag, 1980; 195-201.

    Google Scholar 

  3. Nicoletti L, Verani P, Caciolli S. Central nervous system involvement during infection by Phlebovirus Toscana of residents in natural foci in central Italy (1977-1988). Am J Trop Med 1991; 45: 429–434.

    Google Scholar 

  4. Paci P, Bartalozzi D, Di Pietro M, et al. Virus neurotropi: aspetti clinici di alcune patologie Emergenti. Giorn Mal. Inf Parass 1990; 42: 262–269.

    Google Scholar 

  5. Eritrem R, Vene S, Niklasson B. Incidence of sandfly fever among Swedish United Nation Soldiers on Cyprus during 1985. Am J Trop Med Hyg 1990; 43(2): 207–211.

    Google Scholar 

  6. Eritrem R, Stylianou M, Niklasson B. High prevalence rates of antibody to three sandfly fever virus (Sicilian, Naples andToscana) among Cypriots. Epidemiol Infect 1991; 107: 685–689.

    Google Scholar 

  7. Ehrnst A, Peters CJ, Niklasson B, et al. Neurovirulent Toscana Virus (a sandfly fever virus) in Swedish man after visit to Portugal. The Lancet 1985; 25(1): 1212–1213.

    Google Scholar 

  8. Mendoza-Montero J, Gamez-Rueda MI, Navarro-Mari JM, et al. Infection due to sandfly fever virus serotype Toscana in Spain. Clin Infect Dis 1998; 27: 434–436.

    Google Scholar 

  9. Braito A, Corbisiero R, Corradini S, et al. Evidence of toscana virus infection without central nervous system involvement: A serological study. Eur J Epidemiol 1997; 13: 761–764.

    Google Scholar 

  10. Schwarz TE, Gilem S, Jager G. Travel-relatedToscana virus infection. The Lancet 1993; 25(13): 761–764.

    Google Scholar 

  11. Eritrem R, Nyklasson B, Weiland O. Sandfly fever among Swedish tourists. Scand J Infect Dis 1991; 23: 451–457.

    Google Scholar 

  12. Dobler G, Treib J, Haass A, et al. Toscana virus infection in German travellers returning from the Mediterranean. Infection 1997; 25(5): 325.

    Google Scholar 

  13. Calisher CN, Weinberg AN, Muth DJ, Lazvick JS. Toscana virus infection in United States citizen returning from Italy. The Lancet 1987; 1(8525): 165–166.

    Google Scholar 

  14. Valassina M, Cusi MG, Valensin PE. Rapidid entification of Toscana virus by nested PCR during an outbreak in the Siena area of Italy. J Clin Microbiol 1996; 34: 2500–2502.

    Google Scholar 

  15. Giorgi C, Accardi L, Nicoletti L, et al. Sequences and coding strategies of the S RNAs of Toscana and Rift Valley fever viruses comparedto those Punta Toro, Sicilian sandfly fever and Uukuniemi viruses. Virology 1991; 180: 738–753.

    Google Scholar 

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Francisci, D., Papili, R., Camanni, G. et al. Evidence of Toscana virus circulation in Umbria: First report. Eur J Epidemiol 18, 457–459 (2003). https://doi.org/10.1023/A:1024295710118

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  • DOI: https://doi.org/10.1023/A:1024295710118

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