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Synthesis and Study of Lactim Ethers of 3,4-Dihydrocarbostyryl and 2,3,4,5-Tetrahydrobenz[b]azepin-2-one

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

Alkylation of 3,4-dihydrocarbostyryl and 2,3,4,5-tetrahydrobenz[b]azepin-2-one using dimethyl sulfate and triethyloxonium fluoborate gives the corresponding lactim ethers. The reactions of lactim ethers with different compounds having primary amino groups (including ammonia, alkyl-, aralkyl-, and arylamines, amino acids, and related compounds) have been studied. Novel heterocyclic compounds based on the lactim ethers have been synthesized.

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Golovko, T.V., Solov'eva, N.P., Anisimova, O.S. et al. Synthesis and Study of Lactim Ethers of 3,4-Dihydrocarbostyryl and 2,3,4,5-Tetrahydrobenz[b]azepin-2-one. Chemistry of Heterocyclic Compounds 39, 344–353 (2003). https://doi.org/10.1023/A:1023918911369

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  • DOI: https://doi.org/10.1023/A:1023918911369

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