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References
Ausubel, F. M., Brent, R., Kingston, R. E., et al. (1993). Current Protocols in Molecular Biology, 2nd edn., Greene, New York.
Bech-Otschir, D., Kraft, R., Huang, X., et al. (2001). COP9 signalosome-specific phosphorylation targets p53 to degradation by the ubiquitin system. EMBO J. 20(7):1630–1639.
Cacalano, N. A., Migone, T. S., Bazan, F., et al. (1999). Autosomal SCID caused by a point mutation in the N-terminus of Jak3: Mapping of the Jak3–receptor interaction domain. EMBO J. 18(6):1549–1558.
Dorsch, M., Danial, N. N., Rothman, P. B., et al. (1999). A thrombopoietin receptor mutant deficient in Jak-STAT activation mediates proliferation but not differentiation in UT-7 cells. Blood 94:2676–2685.
Feng, L. B., Yang, L. M., Zhou, W. G., et al. (2001). SGK and 14–3–3 protein are involved in the serine/threonine phosphorylation mechanism for TPO/MPL signal transduction. Chin. Sci. Bull. 46(22): 1880–1884.
Friedrich, K., Kammer, W., Erhardt, I., et al. (1999). Activation of STAT5 by IL-4 relies on Janus kinase function but not on receptor tyrosine phosphorylation, and can contribute to both cell proliferation and gene regulation. Int. Immunol. 11(8):1283–1294.
Fujiwara, H., Hanissian, S. H., Tsytsykova, A., et al. (1997). Homodimerization of the human interleukin 4 receptor alpha chain induces Cepsilon germline transcripts in B cells in the absence of the interleukin 2 receptor gamma chain. Proc. Natl. Acad. Sci. U.S.A. 94(11):5866–5871.
Haan, C., Heinrich, P. C., & Behrmann, I. (2002). Structural requirements of the interleukin-6 signal transducer gp130 for its interaction with Janus kinase 1: The receptor is crucial for kinase activation. Biochem. J. 361(Pt. 1):105–111.
Haznedaroglu, I. C., Arici, M., & Buyukasik, Y. (2000). A unifying hypothesis for the renin–angiotensin system and hematopoiesis: Sticking the pieces together with the JAK-STAT pathway. Med. Hypotheses 54(1):80–83.
Higuchi, M., Asao, H., Tanaka, N., et al. (1997). Regulation of IL-2 signaling. Leukemia 11(Suppl. 3):416–417.
Howard, O. M., Kirken, R. A., Garcia, G. G., et al. (1995). Structural domains of interleukin-2 receptor beta critical for signal transduction: Kinase association and nuclear complex-formation. Biochem. J. 306(Pt. 1):217–224.
Jiang, N., He, T. C., Miyajima, A., et al. (1996). The box 1 domain of the erythropoietin receptor specifies Janus kinase 2 activation and functions mitogenically within an interleukin 2 beta-receptor chimera. J. Biol. Chem. 271(28):16472–16476.
Kaushansky, K., Lok, S., Holly, R. D., et al. (1994). Promotion of megakaryocyte progenitor expansion and differentiation by the c-Mpl ligand thrombopoietin. Nature 369(6481):568–571.
Li, J., & Kuter, D. J. (2001). The end is just the beginning: Megakaryocyte apoptosis and platelet release. Int. J. Hematol. 74(4):365–374.
Liu, R., Itoh, T., Arai, K., et al. (1997). Activation of c-Jun N-terminal kinase by human granulocyte macrophage-colony stimulating factor in BA/F3 cells. Biochem. Biophys. Res. Commun. 234(3):611–615.
Miyakawa, Y., Drachman, J. G., Gallis, B., et al. (2000). A structure–function analysis of serine/threonine phosphorylation of the thrombopoietin receptor, c-Mpl. J. Biol. Chem. 275(41):32214–32219.
Miyakawa, Y., Oda, A., Druker, B. J., et al. (1996). Thrombopoietin induces tyrosine phosphorylation of Stat3 and Stat5 in human blood plates. Blood 87(2):439–446.
Oda, A., Ozaki, K., & Druker, B. J. (1996). P120c-cbl is present in human blood plates and is differentially involved in signaling by thrombopoietin and thrombin. Blood 88(4):1330–1338.
Okabe, S., Tauchi, T., Morita, H., et al. (1999). Thrombopoietin induces an SH2–containing protein, CIS1, which binds to Mpl: Involvement of the ubiquit in proteosome pathway. Exp. Hematol. 27(10):1542–1547.
Prasad, K. V., Ao, Z., Yoon, Y., et al. (1997). CD27, a member of the tumor necrosis factor receptor family, induces apoptosis and binds to Siva, a proapoptotic protein. Proc. Natl. Acad. Sci. U.S.A. 94(12):6346–6351.
Rojnuckarin, P., Drachman, J. G., & Kaushansky, K. (1999). Thrombopoietin induced activation of the mitogen-activated protein kinase (MAPK) pathway in normal megakaryocytes: Role in endomitosis. Blood 94(4):1273–1282.
Sambrook, J., Fretsch, E. F., Maniatis, T. (1989). Molecular Cloning: A Laboratory Manual, 2nd edn., Cold Spring Harbor Laboratory Press, New York.
Schwechheimer, C., & Deng, X. W. (2001). COP9 signalosome revisited: A novel mediator of protein degradation. Trends Cell Biol. 11(10):420–426.
Seroussi, E., Kedra, D., Kost-Alimova, M., et al. (1999). TOM1 genes map to human chromosome 22q13.1 and mouse chromosome 8C1 and encode proteins similar to the endosomal proteins HGS and STAM. Genomics 57(3):380–388.
Takatoku, M., Kametaka, M., Shimizu, R., et al. (1997). Identification of functional domains of the human thrombopoietin receptor required for growth and differentiation of megakaryocytic cells. J. Biol. Chem. 272(11):7259–7263.
Takeda, M., Dohmae, N., Takio, K., et al. (2001). Cell cycle-dependent interaction of Mad2 with conserved box1/2 region of human granulocyte-macrophage colony-stimulating factor receptor common beta c. J. Biol. Chem. 276(45):41803–41809.
Umeshita-Suyama, R., Sugimoto, R., Akaiwa, M., et al. (2000). Characterization of IL-4 and IL-13 signals dependent on the human IL-13 receptor alpha chain 1: Redundancy of requirement of tyrosine residue for STAT3 activation. Int. Immunol. 12(11):1499–1509.
Watanabe, S., Itoh, T., Arai, K. (1996). JAK2 is essential for activation of c-fos and c-myc promoters and cell proliferation through the human granulocyte-macrophage colony-stimulating factor receptor in BA/F3 cells. J. Biol. Chem. 271(21):12681–12686.
Yi, W., Kim, SO., Jiang, J., et al. (1996). Growth hormone receptor cytoplasmic domain differentially promotes tyrosine phosphorylation of signal transducers and activators of transcription 5b and 3 by activated JAK2 kinase. Mol. Endocrinol. 10(11):1425–1443.
Zhu, Y. X., Sun, H. B., Tsang, M. L., et al. (1997). Critical cytoplasmic domains of human interleukin-9 receptor alpha chain in interleukin-9–mediated cell proliferation and signal transduction. J. Biol. Chem. 272(34):21334–21340.
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Yang, L., Feng, L., Huang, L. et al. Identification of the Binding Domain of Signal-Transduction-Related Proteins on c-Mpl. Biochem Genet 41, 201–208 (2003). https://doi.org/10.1023/A:1023381728047
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DOI: https://doi.org/10.1023/A:1023381728047