Skip to main content
Log in

Isolation of Ejaculated Spermatozoa Six Hours After Unsuccessful Testicular Biopsy in Nonobstructive Azoospermia

  • Published:
Journal of Assisted Reproduction and Genetics Aims and scope Submit manuscript

Abstract

Azoospermia, the absence of sperm in ejaculated semen, is the most severe form of male factor infertility and is present in approximately 5% of all investigated infertile couples. The condition is currently classified as obstructive and nonobstructive subgroups. In nonobstructive azoospermia, testicular sperm extraction (TESE) is usually necessary for sperm recovery. This is a case report of pregnancy and subsequent birth of healthy babies following intracytoplasmic sperm injection (ICSI) of ejaculated motile spermatozoa presented 6 h after unsuccessful testicular biopsies in four subsequent in vitro fertilization (IVF) cycles with infertility due to nonobstructive azoospermia.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

References

  1. Van Steirteghem A, Nagy Z, Joris H, Liu J, Staessen C, Smitz J, Wisanto D, Devroey P: High fertilization and implantation rates after intracytoplasmic sperm injection Hum Reprod 1993;8:1061–1066

    Google Scholar 

  2. Palermo G, Joris H, Devroey P, Van SteirteghemAC: Pregnancies after intracytoplasmic sperm injection of single spermatozoon into oocytes. Lancet 1992;340:17–18

    Google Scholar 

  3. Devroey P, Liu J, Tournaye H, Silber SJ, Van SteirteghemAC: Normal fertilization of human oocytes after testicular sperm extraction and intracytoplasmic sperm injection (TESE and ICSI). Fertil Steril 1994;60:639–641

    Google Scholar 

  4. Lahav-Baratz S, Rothschild E, Grach B, Koifman M, Shiloh H, Ishai D, Dirnfeld M: The value of sperm pooling and cryopreservation in patients with transient azoospermia or severe oligoasthenoteratozoospermia. Hum Reprod 2002;17(1):157–160

    Google Scholar 

  5. Monzo A, Kondylis F, Lynch D, Mayer J, Jones E, Nehchiri F, Morshedi M, Schuffner A, Muasher S, Gibbons W, Oehninger S: Outcome of intracytoplasmic sperm injection in azoospermic patients: Stressing the liaison between the urologist and reproductive medicine specialist. Urology 2001;58(1):69–75

    Google Scholar 

  6. Van Steirteghem A, Verheyen G, Tournaye H, et al.: Assisted reproductive technology by intracytoplasmic sperm injection in male-factor infertility. Curr Opin Urol 1996;6:333–339

    Google Scholar 

  7. Brinsden PR: A Textbook of In Vitro Fertilization and Assisted Reproduction, 2nd edn. London, The Parthenon Publishing Group, 1999

    Google Scholar 

  8. Chan PT, SchlegelPN: Diagnostic and therapeutic testis biopsy. Curr Urol Rep 2000;1(4):266–272

    Google Scholar 

  9. Tash JA, Schlegel PN: Histologic effects of testicular sperm extraction on the testicle in men with nonobstructive azoospermia. Urology 2001; 57(2):334–337

    Google Scholar 

  10. Silber SJ: Microsurgical TESE and the distribution of spermatogenesis in non-obstructive azoospermia. Hum Reprod 2000; 15(11): 2278–2284

    Google Scholar 

  11. Friedler S, Raziel A, Schachter M, Strassburger D, Bern O, Ron-El R: Outcome of first and repeated testicular sperm extraction and ICSI in patients with non-obstructive azoospermia. Hum Reprod 2002;17(9):2356–2361

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Zádori, J., Pál, A. & Kaáli, S.G. Isolation of Ejaculated Spermatozoa Six Hours After Unsuccessful Testicular Biopsy in Nonobstructive Azoospermia. J Assist Reprod Genet 20, 160–162 (2003). https://doi.org/10.1023/A:1022985304771

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1023/A:1022985304771

Navigation