Abstract
The population of epithelial cells in the small intestine includes precursor cells of hemopoiesis possessing the ability to form splenic colonies on day 8. Intestinal epithelial cells stimulates proliferative and colony-forming activity of hemopoietic stem cells by producing granulocyte-macrophage colony-stimulating factor.
Similar content being viewed by others
REFERENCES
S. V. Krysov, D. Kh. Kuramshin, S. A. Silkov, et al., Klin. Lab. Diagn., No. 12, 39–43 (2000).
G. K. Khrushchev, Lymphoid Tissue in Reparative and Protective Processes [in Russian], Moscow (1966), pp. 7–24.
I. L. Chertkov and O. A. Gurevich, Hemopoietic Stem Cell and Microenvironment [in Russian], Moscow (1984).
K. W. Beagley and A. J. Husband, Crit. Rev. Immunol., 18, 237–254 (1998).
H. C. Jung, L. Eckmann, S. K. Yang, et al., J. Clin. Invest., 95,No. 1, 55–65 (1995).
L. Lefrancois and L. Puddington, Immunol. Today, 16,No. 1, 16–21 (1995).
J. J. Mattapallil, Z. Smit-McBride, and S. Dandekar, J. Virol., 73,No. 5, 4518–4523 (1999).
A. B. J. Speekenbrink and D. M. V. Parrott, Cell Tissue Kinet., 20, 135–144 (1987).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Sennikov, S.V., Temchura, V.V., Trufakin, V.A. et al. Effects of Granulocyte-Macrophage Colony-Stimulating Factor Produced by Intestinal Epithelial Cells on Functional Activity of Hemopoietic Stem Cells. Bulletin of Experimental Biology and Medicine 134, 548–550 (2002). https://doi.org/10.1023/A:1022952810245
Issue Date:
DOI: https://doi.org/10.1023/A:1022952810245