Skip to main content
Log in

Impact of Technical Difficulties, Choice of Catheter, and the Presence of Blood on the Success of Embryo Transfer—Experience from a Single Provider

  • Published:
Journal of Assisted Reproduction and Genetics Aims and scope Submit manuscript

Abstract

Purpose: To investigate the impact of technical difficulties, choice of catheter, and the presence of blood during embryo transfer on the results of in vitro fertilization and ICSI.

Methods: A cohort of 784 consecutive cycles in 655 in vitro fertilization and ICSI patients were studied.

Results: Negotiating the cervix, using the volsellum, presence of blood on the catheter wall or on the cervix did not affect the results. Changing the catheter and blood on the catheter tip reduced the pregnancy (P < 0.05 and P < 0.05) and implantation rates (P < 0.001 and P < 0.01). The Ultrasoft catheter produced higher pregnancy (P < 0.0005) and implantation rates (P < 0.01) compared to the more rigid Frydman catheter.

Conclusions: Negotiation of the cervix, the use of a volsellum, and the presence of blood on the catheter wall or on the cervix do not affect the results. Changing the catheter and blood on the catheter tip significantly diminish the pregnancy and implantation rates. Soft catheters perform better.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Edwards RG: Clinical approaches to increasing uterine receptivity during human implantation. Hum Reprod 1995;10 (Suppl 2):60–66

    Google Scholar 

  2. Nabi A, Awonuga A, Birch H, Barlow S, Stewart B: Multiple attempts at embryo transfer: Does this affect in-vitro fertilization treatment outcome? Hum Reprod 1997;12:1188–1190

    Google Scholar 

  3. Abusheikha N, Lass A, Akagbosu F, Brinsden P: How useful is cervical dilatation in patients with cervical stenosis who are participating in an in vitro fertilization-embryo transfer program? The Bourn Hall experience. Fertil Steril 1999;72:610–612

    Google Scholar 

  4. Burke LM, Davenport AT, Russell GB, Deaton JL: Predictors of success after embryo transfer: Experience from a single provider. Am J Obstet Gynecol 2000;182:1001–1004

    Google Scholar 

  5. Tur-Kaspa I, Yuval Y, Bider D, Levron J, Shulman A, Dor J: Difficult or repeated sequential embryo transfers do not adversely affect in-vitro fertilization pregnancy rates or outcome. Hum Reprod 1998;13:2452–2455

    Google Scholar 

  6. Dorn C, Reinsberg J, Schlebusch H, Prietl G, van der Ven H, Krebs D: Serum oxytocin concentration during embryo transfer procedure. Eur J Obstet Gynecol Reprod Biol 1999;87:77–80

    Google Scholar 

  7. Lesny P, Killick SR, Robinson J, Raven G, Maguiness SD: Junctional zone contractions and embryo transfer: Is it safe to use a tenaculum? Hum Reprod 1999;14:2367–2370

    Google Scholar 

  8. Visser DS, Fourie FL, Kruger HF: Multiple attempts at embryo transfer: Effect on pregnancy outcome in an in vitro fertilization and embryo transfer program. J Assist Reprod Genet 1993;10:37–43

    Google Scholar 

  9. Goudas VT, Hammitt DG, Damario MA, Session DR, Singh AP, Dumesic DA: Blood on the embryo transfer catheter is associated with decreased rates of embryo implantation and clinical pregnancy with the use of in vitro fertilization-embryo transfer. Fertil Steril 1998;70:878–882

    Google Scholar 

  10. Gonen Y, Dirnfeld M, Goldman S, Koifman M, Abramovici H: Does the choice of catheter for embryo transfer influence the success rate of in-vitro fertilization? Hum Reprod 1991;6:1092–1094

    Google Scholar 

  11. Meriano J, Weissman A, Greenblatt EM, Ward S, Casper RF: The choice of embryo transfer catheter affects embryo implantation after IVF. Fertil Steril 2000;74:678–682

    Google Scholar 

  12. Wood EG, Batzer FR, Go KJ, Gutmann JN, Corson SL: Ultrasound-guided soft catheter embryo transfers will improve pregnancy rates in in-vitro fertilization. Hum Reprod 2000;15:107–112

    Google Scholar 

  13. Wisanto A, Janssens R, Deschacht J, Camus M, Devroey P, Van Steirteghem AC: Performance of different embryo transfer catheters in a human in vitro fertilization program. Fertil Steril 1989;52:79–84

    Google Scholar 

  14. Ghazzawi IM, Al-Hasani S, Karaki R, Souso S: Transfer technique and catheter choice influence the incidence of transcervical embryo expulsion and the outcome of IVF. Hum Reprod 1999;14:677–682

    Google Scholar 

  15. Urman B, Aksoy S, Alatas C, Mercan R, Nuhoglu A, Isiklar A, Balaban B: Comparing two embryo transfer catheters. Use of a trial transfer to determine the catheter applied. J Reprod Med 2000;45:135–138

    Google Scholar 

  16. Al-Shawaf T, Dave R, Harper J, Linehan D, Riley P, Craft I: Transfer of embryos into the uterus: How much do technical factors affect pregnancy rates? J Assist Reprod Genet 1993;10:31–36

    Google Scholar 

  17. Hearns-Stokes RM, Miller BT, Scott L, Creuss D, Chakraborty PK, Segars JH: Pregnancy rates after embryo transfer depend on the provider at embryo transfer. Fertil Steril 2000;74:80–86

    Google Scholar 

  18. Sallam HN, Marinho AO, Collins WP, Rodeck CH, Campbell S. Monitoring: gonadotrophin therapy by real-time ultrasonic scanning of ovarian follicles. Br J Obstet Gynaecol 1982;89:155–159

    Google Scholar 

  19. Edwards RG, Steptoe PC, Purdy J: Establishing full-term human pregnancies using cleaving embryos grown in vitro. Br J Obstet Gynaecol 1980;87:737–756

    Google Scholar 

  20. Palermo G, Joris H, Devroey P, Van Steirteghem AC: Pregnancies after intracytoplasmic injection of single spermatozoon into an oocyte. Lancet 1992;340:17–18

    Google Scholar 

  21. Leeton J, Trounson A, Jessup D, Wood C: The technique for human embryo transfer. Fertil Steril 1982;38:156–161

    Google Scholar 

  22. Edwards RG, Fishel SB, Cohen J, Fehilly CB, Purdy JM, Slater JM, Steptoe PC, Webster JM: Factors influencing the success of in vitro fertilization for alleviating human infertility. J In Vitro Fert Embryo Transf 1984;1:3–23

    Google Scholar 

  23. Noyes N, Licciardi F, Grifo J, Krey L, Berkeley A: In vitro fertilization outcome relative to embryo transfer difficulty: A novel approach to the forbidding cervix. Fertil Steril 1999;72:261–265

    Google Scholar 

  24. Rizk B, Tan SL, Morcos S, Riddle A, Brinsden P, Mason BA, Edwards RG: Heterotopic pregnancies after in vitro fertilization and embryo transfer. Am J Obstet Gynecol 1991;164:161–164

    Google Scholar 

  25. Egbase PE, Al-Sharhan M, Grudzinskas JG: Influence of position and length of uterus on implantation and clinical pregnancy rates in IVF and embryo transfer treatment cycles. Hum Reprod 2000;15:1943–1946

    Google Scholar 

  26. Yovich JL, Turner SR, Murphy AJ: Embryo transfer technique as a cause of ectopic pregnancies in in vitro fertilization. Fertil Steril 1985;44:318–321

    Google Scholar 

  27. Nazari A, Askari HA, Check JH, O'Shaughnessey A: Embryo transfer technique as a cause of ectopic pregnancy in in vitro fertilization. Fertil Steril 1993;60:919–921

    Google Scholar 

  28. Azem F, Yaron Y, Botchan A, Amit A, Yovel I, David MP, Peyser MR, Lessing JB: Ectopic pregnancy after in vitro fertilization-embryo transfer (IVF-ET): The possible role of the ET technique. J Assist Reprod Genet 1993;10:302–304

    Google Scholar 

  29. Lesny P, Killick SR, Robinson J, Maguiness SD: Transcervical embryo transfer as a risk factor for ectopic pregnancy. Fertil Steril 1999;72:305–309

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Sallam, H.N., Agameya, A.F., Rahman, A.F. et al. Impact of Technical Difficulties, Choice of Catheter, and the Presence of Blood on the Success of Embryo Transfer—Experience from a Single Provider. J Assist Reprod Genet 20, 135–142 (2003). https://doi.org/10.1023/A:1022905618883

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1023/A:1022905618883

Navigation