Abstract
The buildup of oxidation products of L-α-phosphatidylcholine, the constituent of liposome lipid bilayers, was studied depending on the qualitative and quantitative composition of radiolytic species formed on irradiation of an aqueous dispersion. The presence of ionol (2,6-di-tert-butyl-4-methylphenol) as a nonselective radical scavenger at a concentration of 2.5 × 10–4 mol/glipid in a lipid bilayer decreased the accumulation of oxidation products by a factor of 3–7.
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Paramonov, D.V., Trofimov, V.I. Radiation-Chemical Oxidation of Molecules in the Lipid Bilayer of Lecithin Liposomes by Radiolytic Products Formed in the Radiolysis of an Aqueous Dispersion. High Energy Chemistry 37, 78–82 (2003). https://doi.org/10.1023/A:1022880231007
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DOI: https://doi.org/10.1023/A:1022880231007