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Detection of repolarization abnormalities in patients with cardiomyopathy using current vector mapping technique on magnetocardiogram

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Abstract

Objectives: We have previously developed current vector maps of tangential components on the magnetocardiogram (MCG) to obtain cardiac current distribution images. The present study was conducted to detect repolarization abnormalities in patients with cardiomyopathy using the current vector map. Subjects and methods: Thirteen patients with cardiomyopathy (nine males and four females aged 7–16 years, mean, 11.5 ± 3.1 years, ±SD), and 15 age- and sex-matched normal subjects were studied. Normal components (Bz) of MCG were measured at rest with a multi-channel superconducting quantum interface device (SQUID) system, and differentiated in the tangential direction to obtain current vector maps. Homogeneity of current in the heart during repolarization was investigated. The direction of the maximum current vector was also calculated in each case. Results: In all normal subjects, the current vector consistently showed a left downward direction on the frontal chest plane during the repolarization process. On the other hand, 8 out of 13 patients with cardiomyopathy showed different patterns; four of these patients showed multi-dipoles, and the other four showed a shift in the current vector direction. One of the eight cases showed no abnormality on electrocardiogram (ECG). Conclusions: Repolarization process in patients with cardiomyopathy was apparently different from those in normal subjects on the current vector map. It was easy to visualize the repolarization process as a projection to the frontal plane, including regional abnormalities, by the current vector maps, which might be more useful for early detection of repolarization abnormalities than ECG.

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Authors and Affiliations

  1. Departments of Pediatrics, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki, 305-8575, Japan

    Junko Shiono, Hitoshi Horigome & Akira Matsui

  2. Cardiovascular Surgery, Institute of Clinical Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki, 305-8575, Japan

    Yasushi Terada

  3. Central Research Laboratory, 1-280 Higashi-Koigakubo, Kokubunji, Hitachi Ltd., Tokyo, 185-8601, Japan

    Tsuyoshi Miyashita & Keiji Tsukada

Authors
  1. Junko Shiono
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  2. Hitoshi Horigome
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  3. Akira Matsui
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  4. Yasushi Terada
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  5. Tsuyoshi Miyashita
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  6. Keiji Tsukada
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Shiono, J., Horigome, H., Matsui, A. et al. Detection of repolarization abnormalities in patients with cardiomyopathy using current vector mapping technique on magnetocardiogram. Int J Cardiovasc Imaging 19, 163–170 (2003). https://doi.org/10.1023/A:1022823217232

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  • DOI: https://doi.org/10.1023/A:1022823217232

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