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Effect of Radiation on Prothrombin Interactions with Cell Membrane Fragments

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Abstract

Binding of 125I-labeled prothrombin to normal and radiation-damaged (1 and 3.5 Gy) fragments of cell membranes was studied. Irradiation significantly increased adsorption capacity of cell membranes for 125I-prothrombin. It was concluded that phase rearrangement of phospholipids serves as the molecular basis for increased thrombogenicity of cell membranes.

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Authors and Affiliations

  1. Kazan State Medical University, Russia

    S. V. Kiselev, D. M. Zubairov & S. V. Kirshin

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  1. S. V. Kiselev
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  2. D. M. Zubairov
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  3. S. V. Kirshin
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Kiselev, S.V., Zubairov, D.M. & Kirshin, S.V. Effect of Radiation on Prothrombin Interactions with Cell Membrane Fragments. Bulletin of Experimental Biology and Medicine 134, 442–444 (2002). https://doi.org/10.1023/A:1022630011907

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  • DOI: https://doi.org/10.1023/A:1022630011907

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