Multifocal electroretinography in central serous chorio-retinopathy and assessment of the reproducibility of the multifocal electroretinography

Abstract

Purpose: To measure and compare the difference of multifocal electroretinography (mERG) in control subjects and patients with central serous chorio-retinopathy(CSCR) and assessing the reproducibility of the multifocal electroretinography. Methods: Sixteen cases of control subjects and 12 cases of central serous chorio-retinopathy were tested with the Visual Evoked Response Imaging System science™4.2 made by EDI company of America. The results of the left eye of each control subject and patient were used for statistical evaluation by the Mann–Whitney U test. Repeat measurements were performed on 11 control subjects. Wilcoxon technique were used to quantify the reproducibility of the test. Results: The P₁ waveform average response density of 1–3 rings in central serous chorio-retinopathy were decreased statistically. There was no significant difference between repeat measurements on 11 individuals. Conclusion: Multifocal electroretinography can be used to quantify the visual function of the affected area in chorio-retinopathy and showed good agreement in the data distribution for the repeat measurements.