Abstract
Condensation of 2-, 3-aminopyridines and 2-aminopyrimidine with 1-vinyl- and 1-ethylimidazole-2-carbaldehydes and 1-vinyl-, 1-ethylbenzimidazole-2-carbaldehydes takes two paths depending on the reagents structure: either form Schiff bases or aminals of the corresponding heterocyclic carbaldehydes.
Similar content being viewed by others
REFERENCES
Belikov, V.G., Farmatsevticheskaya khimiya (Pharmaceutical Chemistry), Moscow: Vysshaya Shkola, 1985.
Lukevits, E. and Ignatovich, L., Geterotsikly na mirovom rynke lekarstvennykh sredstv (Heterocycles on World Marker of Medicines), Riga: Latviiskaya Akad. Nauk, 1992.
Shaimardanova, G.S., Kamburg, R.A., Evstigneeva, R.P., and Sergeeva, N.V., Khim.-Farm. Zh., 1992, vol. 26, no. 3, pp. 31-38.
Spasov, A.A., Iezhitsa, I.N., and Bugaeva, L.M., Khim. Farm. Zh., 1999, vol. 33, no. 5, pp. 6-17.
Popova, I.Yu., Lazareva, D.N., and Zarudii, F.S., Eksperiment. i klinich. farmakologiya, 1996, vol. 59, no. 3, pp. 72-77.
Kodera, M., Terasako, N., Kita, T., Tachi, Y., Kano, K., Yamazaki, M., Koikawa, M., and Tokii, T., Inorg. Chem., 1997, vol. 36, no. 18, pp. 3861-3868.
Mishnev, A., Iovel, I., Popelis, J., Vosekalna, I., and Lukevics, E., J. Organometal. Chem., 2000, vol. 608, pp. 1-5.
Baikalova, L.V., Sobenina, L.N., Mikhaleva, A.I., Zyryanova, I.A., Chipanina, N.N., Afonin, A.V., and Trofimov, B.A., Zh. Org. Khim., 2001, vol. 37, no. 12, pp. 1817-1821.
Baikalova, L.V., Afonin, A.V., and Domnina, E.S., Izv. Akad. Nauk, Ser. Khim., 1997, no. 10, pp. 1857-1859.
Baikalova, L.V., Domnina, E.S., Chipanina, N.N., Afonin, A.V., and Shulunova, A.M., Izv. Akad. Nauk, Ser. Khim., 1999, no. 5, pp. 971-974.
Comprehensive Organic Chemistry, Barton, D. and Ollisa, U., Eds., Oxford: Pergamon Press, 1984.
Obshchii praktikum po organicheskoi khimii (General Practicum on Organic Chemistry), Kost, A.N., Ed., Moscow: Mir, 1965, p. 373.
Baikalova, L.V., Domnina, E.S., Kashik, T.V., Gavrilova, G.A., Kukhareva, V.A., Afonin, A.V., and Mamaseva, T.V., Zh. Obshch. Khim., 1988, vol. 68, no. 5, pp. 842-847.
Baikalova, L.V., Gavrilova, G.A., Chipanina, N.N., and Turchaninov V.K., Zh.Obshch. Khim., 2000, vol. 70, no. 3, pp. 469-474.
Stern, E.S. and Timmons, C.J., Introduction to Electronic Absorption Spectroscopy in Organic Chemistry, London: Edward Arnold, 1970.
Afonin, A.V., Baikalova, L.V., and Domnina, E.S., Izv. Akad. Nauk, Ser. Khim., 1996, no. 5, pp. 1197-1201.
Afonin, A.V., Danovich, D.K., Voronov, V.K., Es'kova, L.A., Baikalova, L.V., and Domnina, E.S., Khim. Geterotsikl. Soed., 1990, no. 10, pp. 1346-1351.
Afonin, A.V., Domnina, E.S., Baikalova, L.V., and Voronov, V.K., Izv. Akad. Nauk, Ser. Khim., 1990, no. 12, pp. 2747-2750.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Baikalova, L.V., Zyryanov, I.A., Afonin, A.V. et al. Features of 2-, 3-Aminopyridines and 2-Aminopyrimidine Condensation with 2-Formylimidazoles. Russian Journal of Organic Chemistry 38, 1674–1680 (2002). https://doi.org/10.1023/A:1022578505237
Issue Date:
DOI: https://doi.org/10.1023/A:1022578505237