Abstract
Purpose: The chance of recurrence of poor fertilization in a second in vitro fertilization (IVF) cycle was assessed.
Methods: Total fertilization failure was defined, and the relationship between the fertilization rate and the number of motile sperm cells per milliliter of semen was assessed. Patients with a total fertilization failure or poor fertilization (20% or less of the oocytes fertilized) were divided into three subgroups with different chances of fertilization and were followed in a subsequent IVF cycle.
Results: The recurrence rate of total fertilization failure was high in all three groups (45–70%), and poor fertilization frequently occurred in the second cycle (50–75%).
Conclusions: Poor fertilization frequently recurs in the second IVF cycle. The use of intracytoplasmic sperm injection could be considered after fertilization of 20% or less of oocytes in the first cycle, irrespective of the number of motile sperm cells per milliliter of semen.
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Roest, J., van Heusden, A.M., Zeilmaker, G.H. et al. Treatment Policy After Poor Fertilization in the First IVF Cycle. J Assist Reprod Genet 15, 18–21 (1998). https://doi.org/10.1023/A:1022570120207
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DOI: https://doi.org/10.1023/A:1022570120207