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Synthesis of Ethophenprox

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Abstract

An ethophenprox synthesis from easily available p-nitroneophyl chloride was developed. The reduction of the latter to aniline derivative followed by Sandmayer's and Claisen's reactions furnished p-ethoxyneophyl chloride that by condensation with 3-phenoxybenzyl alcohol in the presence KOH in DMSO yielded ethophenprox.

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Rakhimov, R.G., Galin, F.Z., Tomilov, Y.V. et al. Synthesis of Ethophenprox. Russian Journal of Organic Chemistry 38, 1629–1634 (2002). https://doi.org/10.1023/A:1022562101602

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