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A novel cross-linking reagent for bovine hemoglobin modification

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Abstract

A novel cross-linking reagent, methoxypolyethelene glycol-glutamic acid, was synthesized and used to modify bovine hemoglobin. Bis-tetrameric hemoglobin with moderate affinity for O2 was obtained under the controlled reaction conditions.

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Authors and Affiliations

  1. National Laboratory of Biochemical Engineering, Institute of Process Engineering, Chinese Academy of Sciences, P.O. Box 353, Beijing, 100080, P.R. China

    Minglei He, Xiuling Lu, Dongxu Zhao & Zhiguo Su

Authors
  1. Minglei He
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  2. Xiuling Lu
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  3. Dongxu Zhao
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  4. Zhiguo Su
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He, M., Lu, X., Zhao, D. et al. A novel cross-linking reagent for bovine hemoglobin modification. Biotechnology Letters 25, 327–330 (2003). https://doi.org/10.1023/A:1022353711956

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  • DOI: https://doi.org/10.1023/A:1022353711956

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