Skip to main content
SpringerLink
Log in

Adjunctive Use of Olanzapine in Mood Disorders: Five Case Reports

  • Published:
Annals of Clinical Psychiatry

Abstract

Olanzapine has emerged as an atypical antipsychotic with few side effects and potentially superior efficacy in the treatment of schizophrenia. To our knowledge there have been few published reports of olanzapine in the treatment of mood disorders. We report on the adjunctive use of this medication in three subjects with mania and two with depression. Response occurred rapidly and patients tolerated the medication. Olanzapine offers promise in the treatment of mood disorders.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

REFERENCES

  1. Weiden P, Aquila R, Standard J: Atypical antipsychotic drugs and long-term outcome in schizophrenia. J Clin Psychiatry 1996; 57(Suppl 11):53–60

    Google Scholar 

  2. Tran PV, Tollefson G, Hamilton S, et al.: Olanzapine vs. risperidone in the treatment of psychosis. Preliminary report. Presented at the American College of Neuropsychiatry; December 9–13, 1996, Abstract 255

  3. Sanger TM, Tollefson G, Lieberman JA: Olanzapine versus haloperidol in the treatment of first episode psychosis. Presented at the American College of Neuropsychiatry; December 9–13, 1996, Abstract 254

  4. Shopsin B, Gershon S, Thompson H, et al.: Psychoactive drugs in mania: A controlled comparison of lithium carbonate, chlorpromazine, and haloperidol. Arch Gen Psychiatry 1975; 32:34–42

    Google Scholar 

  5. Prien RF, Caffey EM Jr, Klett CJ: Comparison of lithium carbonate and chlorpromazine in the treatment of mania: Report of the Veterans Administration and National Institute of Mental Health Collaborative Study Group. Arch Gen Psychiatry 1972; 26:146–153

    Google Scholar 

  6. Takahashi R, Sakuma A, Itoh K, et al.: Comparison of efficacy of lithium carbonate and chlorpromazine in mania: Report of collaborative study group on treatment of mania in Japan. Arch Gen Psychiatry 1975; 32:1310–1318

    Google Scholar 

  7. Kukopulos A, Tondo L: Lithium non-responders and their treatment. In: Johnson FN, ed. Handbook of Lithium Therapy. Baltimore: University Park Press; 1980:143–149

    Google Scholar 

  8. Morgan HG: The incidence of depressive symptoms during recovery from hypomania. Br J Psychiatry 1972; 120:537–539

    Google Scholar 

  9. McElroy SA, Keck PE, Strakowski SM: Mania, psychosis, and antipsychotics. J Clin Psychiatry 1996; 57(Suppl 3):14–23

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Psychiatry and Behavioral Science, Duke University Medical Center Durham, North Carolina

    Richard H. Weisler, Eileen R Ahearn & Jonathan R. T. Davidson

  2. Private Practice, Raleigh, North Carolina

    Richard H. Weisler, Eileen R Ahearn & Charles D. Wallace

Authors
  1. Richard H. Weisler
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Eileen R Ahearn
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Jonathan R. T. Davidson
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Charles D. Wallace
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Weisler, R.H., Ahearn, E.R., Davidson, J.R.T. et al. Adjunctive Use of Olanzapine in Mood Disorders: Five Case Reports. Ann Clin Psychiatry 9, 259–262 (1997). https://doi.org/10.1023/A:1022312612221

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1023/A:1022312612221

Search

Navigation