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The 1(2)-Dehydrogenation of Steroid Substrates by Nocardioides simplex VKM Ac-2033D

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Abstract

The bacterium formerly known asArthrobacter globiformis 193 has high 1(2)-dehydrogenase activity toward pharmaceutically important steroids, 9(11)-dehydrocortexolone in particular. The complex analysis of the morphostructural, physiological, biochemical, and phylogenetic properties of this bacterium allowed us to reclassify it into Nocardioides simplex (N. simplex VKM Ac-2033D).

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Authors and Affiliations

  1. Skryabin Institute of Biochemistry and Physiology of Microorganisms, Russian Academy of Sciences, pr. Nauki 5, Pushchino, Moscow oblast, 142290, Russia

    V. V. Fokina, G. V. Sukhodol'skaya, S. A. Gulevskaya, E. Yu. Gavrish, L. I. Evtushenko & M. V. Donova

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  1. V. V. Fokina
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  2. G. V. Sukhodol'skaya
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  3. S. A. Gulevskaya
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  4. E. Yu. Gavrish
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  5. L. I. Evtushenko
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  6. M. V. Donova
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Fokina, V.V., Sukhodol'skaya, G.V., Gulevskaya, S.A. et al. The 1(2)-Dehydrogenation of Steroid Substrates by Nocardioides simplex VKM Ac-2033D. Microbiology 72, 24–29 (2003). https://doi.org/10.1023/A:1022265720470

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  • DOI: https://doi.org/10.1023/A:1022265720470

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