Abstract
Reactions between p-methylanisole, isobutyraldehyde, and nitriles (acetonitrile, methyl thiocyanate, or ethyl cyanoacetate) in conc. H2SO4 yield 1-substituted (R,S)-8-(2-methoxy-5-methylphenyl)-3,3,9-trimethyl-2-azaspiro[4.5]deca-1,7-dien-6-ones.
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V. A. Glushkov, Yu. V. Shklyaev, V. I. Sokol, V. V. Davidov, and V. S. Sergienko, Mendeleev Commun., 1998, 227.
V. A. Glushkov, Yu. V. Shklyaev, V. I. Sokol, V. V. Davidov, and V. S. Sergienko, Mendeleev Commun., 1999, 170.
V. A. Glushkov, O. G. Ausheva, and Yu. V. Shklyaev, Khim. Geterotsikl. Soedin., 2000, 693 [Chem. Heterocycl. Compd., 2000, No. 5 (Engl. Transl.)].
V. A. Glushkov, O. G. Ausheva, G. A. Postanogova, and Yu. V. Shklyaev, Khim. Geterotsikl. Soedin., 2000, 1559 [Chem. Heterocycl. Compd., 2000, No. 11 (Engl. Transl.)].
V. A. Glushkov and Yu. V. Shklyaev, Mendeleev Commun., 1998, 17.
Yu. V. Shklyaev and Yu. V. Nifontov, Izv. Akad. Nauk, Ser. Khim., 2002, 780 [Russ. Chem. Bull., Int. Ed., 2002, 51, 844].
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Shklyaev, Y.V., Nifontov, Y.V., Shashkov, A.S. et al. Synthesis of 1-substituted (R,S)-8-(2-methoxy-5-methylphenyl)-3,3,9-trimethyl-2-azaspiro[4.5]deca-1,7-dien-6-ones. Russian Chemical Bulletin 51, 2234–2237 (2002). https://doi.org/10.1023/A:1022183318380
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DOI: https://doi.org/10.1023/A:1022183318380