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Adsorption and Activity of Proteins onto Mesoporous Silica

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Abstract

The adsorption and activity of cytochrome c onto two different MCM-41 materials, MCM-41/28 and MCM-41/45 with average pore diameters of 28 and 45 Å respectively, is presented. Nitrogen gas adsorption/desorption isotherms before and after protein adsorption, and peroxidative activity profiles of the adsorbed protein demonstrate that the protein is adsorbed into the mesoporosity and remains active. The adsorption of a range of different proteins onto both MCM-41/28 and 45 shows how protein properties affect adsorption.

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Correspondence to B.K. Hodnett.

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Deere, J., Magner, E., Wall, J. et al. Adsorption and Activity of Proteins onto Mesoporous Silica. Catalysis Letters 85, 19–23 (2003). https://doi.org/10.1023/A:1022156405117

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