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Studies with Polyfunctionally Substituted Heterocycles: Syntheses of Polyfunctionally Substituted Isoquinolines

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

The three-component reaction of acetaldehyde, cyanothioacetamide, and malononitrile results in 6-amino-3,5-dicyano-4-methylpyridine-2(1H)-thione. The latter reacts with different chemical reagents to afford new substituted isoquinolines and their fused derivatives, which show high fungicidal and bactericidal activities.

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Authors and Affiliations

  1. Department of chemistry, Faculty of Science, Helwan University, AinHewan, Cairo-, Egypt

    Y. M. Elkholy

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  1. Y. M. Elkholy
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Elkholy, Y.M. Studies with Polyfunctionally Substituted Heterocycles: Syntheses of Polyfunctionally Substituted Isoquinolines. Chemistry of Heterocyclic Compounds 38, 1342–1347 (2002). https://doi.org/10.1023/A:1022126409122

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