Abstract
The bromination of 5-alkyl(aryl)-3H-furan-2-ones and 5-alkyl(aryl)-3H-pyrrol-2-ones and also their derivatives takes place at the ethylene bond with the formation of 4-monobromo derivatives. N-Phenyl-3H-pyrrol-2-ones are brominated simultaneously at the ethylene bond of the heterocycle and at the phenyl substituent at the nitrogen atom.
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REFERENCES
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V. A. Sedavkina, N. A. Morozova, A. Yu. Egorova, and R. G. Savkin, Izv. Akad. Nauk, Ser. Khim., 1995 (1995).
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Egorova, A.Y., Sedavkina, V.A. Bromination of 5-Substituted 3H-Furan-2-ones and 3H-Pyrrol-2-ones. Chemistry of Heterocyclic Compounds 38, 1319–1323 (2002). https://doi.org/10.1023/A:1022118107304
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DOI: https://doi.org/10.1023/A:1022118107304