Abstract
The paper describes the scientific career of Professor John Newport Langley, an outstanding English physiologist and histologist, member of the London Royal Society and its Vice-President. The main scientific achievements of Langley are dealing with anatomy and physiology of the autonomic (vegetative) nervous system that he considered as an entirely efferent system. The autonomic nervous system was divided by Langley into three parts: sympathetic, parasympathetic, and enteral (intestinal) systems. He has also established functional differences of the autonomic nervous system from the somatic one. He suggested the presence of synaptic contacts on muscle and secretory cells, as well as the existence in these synaptic structures of a peculiar receptor substance providing interaction of nerve fibers with postganglionic neurons and effector cells of visceral organs. The examples of development of several Langley's concepts at present are given.
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REFERENCES
Langley, J.N., The Arrangement of the Sympathetic Nervous System, Based Chiefly on Observation upon Pilomotor Nerves, J. Physiology, 1893, vol. 15, pp. 176–244.
Langley, J.N., On Axon-Reflexes in the Preganglionic Fibers of the Sympathetic System, J. Physiology, 1900, vol. 25, pp. 364–398.
Langley, J.N., On the Contraction of Muscle, Chiefly in Relation to the Presence of Receptive Substances (in Four Parts), J. Physiology, 1907, vol. 36, pp. 347–384; 1908, vol. 37, pp. 165.212, 285.300; 1909, vol. 39, pp. 255.295.
Langley, J.N., Observations on Denervated Muscle, J. Physiology, 1916, vol. 50, pp. 335–344.
Langley, J.N., Antidromic Action, J. Physiology, 1923, vol. 57, pp. 428–446.
Langley, J.N., The Autonomic Nervous System, Part I, Cambridge, 1921.
Langley, J.N. and Orbeli, L.A., Observation on the Sympathetic and Sacral Autonomic System of the Frog, J. Physiology, 1910, vol. 41 pp. 50–482.
Langley, J.N. and Orbeli, L.A., The Sympathetic Innervation of the Viscera, J. Physiology, 1910, vol.41, pp. 66–67.
Bagaev, V.A., Nozdrachev, A.D., and Panteleev, S.S., Vago-vagal.naya reflektornaya duga. Elementy strukturno-funktsional.noi organizatsii (Vago-Vagal Reflex Arc. The Elements of Its Structural and Functional Organization), St. Petersburg, 1997.
Bulygin, I.A., Zamykatel.naya i retseptornaya funktsiya vegetativnykh gangliev (Closing and Receptor Function of Vegetative Ganglia), Minsk, 1964.
Bulygin, I.A. and Kalyunov, V.N., Retheptornaya funktsiya simpaticheskikh gangliev (Receptor Function of Sympathetic Ganglia), Minsk, 1974.
Bulygin, I.A. and Soltanov, V.V., Elektrofiziologicheskii analiz vistseral.nykh afferentnykh sistem (Electrophysiological Analysis of Visceral Afferent Systems), Minsk, 1973.
Lavrent'ev, B.I., Sensory Innervation of Visceral Organs, Zh. Obshch. Biol., 1943, vol. 4, pp. 332–346.
Nozdrachev, A.D., Vegetativnaya reflektornaya duga (Vegetative Reflex Arc), Leningrad, 1978.
Nozdrachev, A.D., Fiziologiya vegetativnoi nervnoi sistemy (Physiology of Vegetative Nervous System), Leningrad, 1983.
Nozdrachev, A.D., On Structural-Functional Organization of the Vegetative (Autonomic) Nervous System, Fiziol. Zh. SSSR im. I.M. Sechenova, 1980, vol. 64, pp. 937–961.
Nozdrachev, A.D., Some Elements of Construction of the Theory of the Metasympathetic Nervous System, Fiziol. Zh. SSSR im. I.M. Sechenova, 1987, vol. 73, pp. 190–201.
Nozdrachev, A.D., Two Viewpoints on the Metasympathetic Nervous System, Fiziol. Zh. SSSR im. I.M. Sechenova, 1991, vol. 77, no. 9, pp. 21–38.
Nozdrachev, A.D., Axon-Reflex. New Viewpoints in the Old Field, Fiziol. Zh. SSSR im. I.M. Sechenova, 1995, vol. 81, no. 11, pp. 135–142.
Nozdrachev, A.D., Bazhenov, Yu.I., Barannikova, I.A., et al., Nachala fiziologii (Basic Physiology), St. Petersburg, 2001.
Nozdrachev, A.D. and Chernysheva, M.P., Vistseral-nye refleksy (Visceral Reflexes), Leningrad, 1989.
Nozdrachev, A.D. and Chumasov, E.I., Perifericheskaya nervnaya sistema (Peripheral Nervous System), St. Petersburg, 1999.
Nozdrachev, A.D. and Fateev, M.M., Zvezdchatyi ganglii (Stellate Ganglion), St. Petersburg, 2002.
Orbeli, L.A., J.N. Langley. In memoriam, Izv. Gos. Nauchno-issled. Inst. im. P.F. Lesgafta, 1927, vol. 12, issue 2, pp. 5–13.
Sokovnin, N.M., Materials for Physiology of Excretion and Retention of Urine, Uch. Zap. Kazansk. Unta, 1877, vol. 44, pp. 1243–1283.
Chernigovskii, V.N., Afferentnye sistemy vnutrennikh organov (Afferent Systems of Visceral Organs), Kirov, 1943.
Chernigovskii, V.N., Interotseptory (Interoreceptors), Moscow, 1960.
Kulyabko, A.A., To Memory of J. N. Langley, Usp. Eksperim. Biol., 1927, vol. VI, issues 1–2, pp. 80–85.
Leibson, L.G., Leon Abgarovich Orbeli (Leon Abgarovich Orbeli), Leningrad, 1973.
Langley, J.N., On the Physiology of the Salivary Secretion (in Six Parts), J. Physilogy, 1878, vol. 1, pp. 96–103, 339.369; 1885, vol. 6, pp. 71.92; 1888, vol. 9, pp. 5.64; 1889, vol. 10, pp. 291.328; 1890, vol. 11, pp. 123.158.
Gaskell, H.W., The Involuntary Nervous System, London, 1920.
Chernigovskii, V.N., Neirofiziologicheskii analiz kortiko-vistseral.noi reflektornoi dugi (Neurophysiological Analysis of the Cortico-Visceral Reflex Arc), Leningrad, 1967.
Skok, V.I., Fiziologiya vegetativnykh gangliev (Physiology of Vegetative Ganglia), Leningrad, 1970.
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Nozdrachev, A.D. John Newport Langley and His Construction of the Autonomic (Vegetative) Nervous System. Journal of Evolutionary Biochemistry and Physiology 38, 537–546 (2002). https://doi.org/10.1023/A:1022056815191
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DOI: https://doi.org/10.1023/A:1022056815191
Keywords
- Nervous System
- Nerve Fiber
- Effector Cell
- Autonomic Nervous System
- Royal Society