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Medication Noncompliance in Adolescents with Psychiatric Disorders

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Abstract

The purpose of the study was to estimate prevalence of medication non-compliance among adolescents, following discharge from hospital. A second purpose was to identify predictors of such noncompliance. Seventy-one adolescents, who had been prescribed a medication during psychiatric hospitalization, were interviewed by telephone, 6–8 months post-hospitalization. Medication noncompliance was defined as discontinuing medication without the recommendation of the treating physician. Twenty-four subjects (33.8%) were noncompliant with medication. Age, race, gender, SES, diagnosis, type and number of medications, severity of depression, and family living arrangement did not predict noncompliance. We concluded that noncompliance with psychotropic medications was relatively common and difficult to predict in adolescents who had been hospitalized to a psychiatric inpatient unit; the majority of them suffered from depression. Clinicians should be aware that medication noncompliance may be common and a relatively unpredictable phenomenon.

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References

  1. Korsch BM, Fine RN, Negrete VF: Noncompliance in children with renal transplants. Pediatrics 61:872-876, 1978.

    Google Scholar 

  2. Smith SD, Rosen D, Trueworthy RC, et al: A reliable method for evaluating drug compliance in children with cancer. Cancer 43:169-173, 1979.

    Google Scholar 

  3. Sleator EK, Ullmann RK, von Neumann A: How do hyperactive children feel about taking stimulants and will they tell the doctor? Clinical Pediatrics 21:474-479, 1982.

    Google Scholar 

  4. Lloyd A, Horan W, Borgaro SR, Stokes JM, Pogge DL, Harvey PD: Predictors of medication compliance after hospital discharge in adolescent psychiatric patients. Journal of Child and Adolesc Psychopharmacology, 8,2, 133-141, 1998.

    Google Scholar 

  5. Webster-Stratton C: Predictors of treatment outcome in parent training for conduct disordered children. Behavior Therapy 16:223-243, 1985.

    Google Scholar 

  6. Dumas JE, Wahler RG: Predictors of treatment outcome in patient training: Mother insularity and socioeconomic disadvantage. Behavioral Assessment 5:301-313, 1983.

    Google Scholar 

  7. Haynes RB, Sackett DL, Gibbon ES, et al: Improvement of medication compliance in uncontrolled hypertension. Lancet 1:1265-1268, 1976.

    Google Scholar 

  8. Fletcher SW, Pappius EM, Harper SJ: Measurement of compliance in a clinical setting. Arch. Int. Med., 139:635-638, 1979.

    Google Scholar 

  9. Bergman AB, Werner RJ: Failure of children to receive penicillin by mouth. New Eng J. Med., 268:13334, 1963.

    Google Scholar 

  10. Gordis L, Markowitz M, Lilienfeld A: Why patients don't follow medical advise: A study of children on long-term antistreptococcal prophylaxis. Journal of Pediatrics 75:957-68, 1969a.

    Google Scholar 

  11. Aneshensel CS, Freichs RR, Clark VA, & Yokopenic PA: Measuring depression in the community: A comparison of telephone and personal interviews. Public Opinion Quarterly, 46, 110-121, 1982.

    Google Scholar 

  12. Hollingshead AB, Redlich F: Social class and mental illness. New York: Wiley, 1958.

    Google Scholar 

  13. Costello EJ, Edelbrock CS, Costello AJ: Validity of the NIMH Diagnostic Interview Schedule for Children: A comparison between psychiatric and pediatric referrals. Journal of Abnormal Child Psychology 13:579-595, 1985.

    Google Scholar 

  14. Poznanski E, Mokros HB, Grossman J, et al: Diagnostic criteria in childhood depression. American Journal of Psychiatry 142:1168-1173, 1985.

    Google Scholar 

  15. Reynolds WM: Reynolds Adolescent Depression Scale: Professional Manual. Odessa, Florida: Psychological Assessment Resources, 1987.

    Google Scholar 

  16. Reynolds WM: Suicidal Ideation Questionnaire: Professional Manual. Odessa, Florida: Psychological Assessment Resources, 1988.

    Google Scholar 

  17. American Psychiatric Association: Diagnostic and Statistical Manual of Mental Disorders, 3rd edition-revised (DSM-III-R). Washington, DC: American Psychiatric Association, 1987

    Google Scholar 

  18. King CA, Hovey JD, Brand E, et al (1997): Prediction of positive outcomes for adolescents psychiatric inpatients hospitalized adolescents. Journal of the American Academy of Child and Adolescent Psychiatry 36:10,1434-1442.

    Google Scholar 

  19. Williams RA, Hollis HM, Benoit K: Attitudes Toward psychiatric medications among incarcerated female adolescents. J. Am. Acad. Child Adolesc. Psychiatry, 37:12, 1301-1307, 1988.

    Google Scholar 

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Ghaziuddin, N., King, C.A., Hovey, J.D. et al. Medication Noncompliance in Adolescents with Psychiatric Disorders. Child Psychiatry Hum Dev 30, 103–110 (1999). https://doi.org/10.1023/A:1021950301932

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  • DOI: https://doi.org/10.1023/A:1021950301932

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