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Effect of Lipid Matrix and Cytoskeleton Proteins on Ca2+-Activated K+Channels in Erythrocytes of Alcoholic and II Type Diabetes Mellitus Patients

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Abstract

We studied the effect of changes in erythrocyte volume and irreversible thermal denaturation of cytoskeleton proteins and lipid matrix on activity of Ca2+-activated K+ channels in erythrocytes of alcoholic and patients with II type diabetes mellitus. Changes in Ca2+-dependent potassium permeability of erythrocyte membrane in alcoholic patients and patients with II type diabetes mellitus are related to modification of cytoskeleton, rather than to changes in lipid matrix.

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REFERENCES

  1. S. N. Orlov, I. V. Petrova, N. I. Pokudin, et al., Biol. Membr., 9,No. 9, 885–904 (1992).

    Google Scholar 

  2. M. Apovo, V. Benzard, F. Galacteros, et al., Biochim. Biophys. Acta., 1225,No. 3, 255–258 (1994).

    Google Scholar 

  3. A. Boldyrev, O. Lopina, V. Prokopjeva, et al., Biochem. Int., No. 3, 297–305 (1983).

  4. C. Brugnara, Experientia, 49, 100–109 (1993).

    Google Scholar 

  5. C. Brugnara, C. C. Armsby, and L. De Francenshi, J. Membr. Biol., 147,No. 1, 71–82 (1995).

    Google Scholar 

  6. C. Brugnara and D. C. Tosteson, Am. J. Physiol., 252,No. 3, Pt. 1, C269–C276 (1987).

    Google Scholar 

  7. R. A. Dodson, T. R. Hinds, and F. F. Vincenzi, Blood Cells, 12, 555–561 (1987).

    Google Scholar 

  8. F. R. Homaidan, L. J. Kricka, A. R. Bailey, and T. P. Whitehead, Ibid., 11,No. 3, 375–392 (1986).

    Google Scholar 

  9. J. H. Johnson and B. P. Crider, Proc. Natl. Acad. Sci. USA, 86, 7857–7860 (1989).

    Google Scholar 

  10. P. Miossec, F. Zkhiri, and J. Paries, Diabet. Med., 16, 424–430 (1999).

    Google Scholar 

  11. S. N. Orlov, N. I. Pokudin, Y. V. Kotelevtsev, and R. V. Gulak, J. Membrane Biol., 107, 105–117 (1989).

    Google Scholar 

  12. V. L. Shnyrov, S. N. Orlov, G. G. Zhadan, and N. I. Pokudin, Biomed. Biochim. Acta., 49,No. 6, 445–453 (1990).

    Google Scholar 

  13. G. Showoch and H. Passow, Mol. Cell. Biochem., 2,No. 2, 197–217 (1973).

    Google Scholar 

  14. I. Testa, A. R. Rabini, and P. Fumelli, J. Clin. Endocrinol. Metab., 67,No. 6, 1129–1133 (1990).

    Google Scholar 

  15. J. M. Vanderkooi and J. B. Calles, Biochemistry, 13, 4000–4006 (1974).

    Google Scholar 

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Prokop'eva, V.D., Petrova, I.V., Sitozhevskii, A.V. et al. Effect of Lipid Matrix and Cytoskeleton Proteins on Ca2+-Activated K+Channels in Erythrocytes of Alcoholic and II Type Diabetes Mellitus Patients. Bulletin of Experimental Biology and Medicine 134, 345–348 (2002). https://doi.org/10.1023/A:1021948012581

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  • DOI: https://doi.org/10.1023/A:1021948012581

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